Accelerated lung aging and chronic obstructive pulmonary disease

YS Yoon, M Jin, DD Sin - Expert review of respiratory medicine, 2019 - Taylor & Francis
Introduction: The prevalence of chronic obstructive pulmonary disease (COPD) increases
exponentially with aging. Its pathogenesis, however, is not well known and aside from …

Senescence in COPD and its comorbidities

PJ Barnes - Annual review of physiology, 2017 - annualreviews.org
Chronic obstructive pulmonary disease (COPD) is regarded as a disease of accelerated
lung aging. This affliction shows all of the hallmarks of aging, including telomere shortening …

Chronic obstructive pulmonary disease and the hallmarks of aging

SP Kukrety, JD Parekh, KL Bailey - Lung India, 2018 - journals.lww.com
Aging is characterized by progressive deterioration of physiological integrity, decline in
homeostasis, and degeneration of the tissues that occurs after the reproductive phase of life …

Targeting aging pathways in chronic obstructive pulmonary disease

M Easter, S Bollenbecker, JW Barnes… - International journal of …, 2020 - mdpi.com
Chronic obstructive pulmonary disease (COPD) has become a global epidemic and is the
third leading cause of death worldwide. COPD is characterized by chronic airway …

Can we delay the accelerated lung aging in COPD? Anti-aging molecules and interventions

AI Papaioannou, C Rossios, K Kostikas… - Current Drug …, 2013 - ingentaconnect.com
Chronic obstructive pulmonary disease (COPD) has been recently characterized as a
disease of accelerated lung aging. The prevalence of COPD is age-dependent suggesting …

Senescence: pathogenic driver in chronic obstructive pulmonary disease

M Rivas, G Gupta, L Costanzo, H Ahmed, AE Wyman… - Medicina, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is recognized as a disease of accelerated
lung aging. Over the past two decades, mounting evidence suggests an accumulation of …

Is chronic obstructive pulmonary disease an accelerated aging disease?

W MacNee - Annals of the American Thoracic Society, 2016 - atsjournals.org
Aging is one of the most important risk factors for most chronic diseases. The worldwide
increase in life expectancy has been accompanied by an increase in the prevalence of age …

Cellular senescence in chronic obstructive pulmonary disease: multifaceted and multifunctional

VB Antony, VJ Thannickal - American journal of respiratory cell and …, 2018 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is characterized by unrelenting airway
inflammation, loss of alveolar-capillary units, and a progressive decline in lung function …

Does lung aging have an impact on chronic obstructive pulmonary disease?

K Ito - Journal of Organ Dysfunction, 2007 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory airway disease. It
has become one of the commonest diseases worldwide and a major global healthcare …

Accelerated lung aging: a novel pathogenic mechanism of chronic obstructive pulmonary disease (COPD)

W MacNee - Biochemical Society Transactions, 2009 - portlandpress.com
An enhanced or abnormal inflammatory response to the lungs to inhaled particles and
gases, usually from cigarette smoke, is considered to be a general pathogenic mechanism …