Effects of stem cell–derived exosome therapy on erectile dysfunction: a systematic review and meta-analysis of preclinical studies

Y Zhu, T Jiang, C Yao, J Zhang, C Sun, S Chen… - Sexual …, 2023 - academic.oup.com
Introduction Erectile dysfunction (ED) is a common disease among elderly men, and novel
therapy methods are needed for drug-refractory ED. As an extracellular vesicle, stem cell …

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

X Ouyang, X Han, Z Chen, J Fang, X Huang… - Stem cell research & …, 2018 - Springer
Background This study investigated the therapeutic effects of MSC-derived exosomes (MSC-
Exos) on erectile function in a rat model of cavernous nerve injury (CNI). Methods MSCs …

Adipose-derived stem cell-derived exosomes ameliorate erectile dysfunction in a rat model of type 2 diabetes

F Chen, H Zhang, Z Wang, W Ding… - The journal of sexual …, 2017 - academic.oup.com
Background The efficacy of adipose-derived stem cells (ADSCs) in alleviating erectile
dysfunction (ED) of diabetic rats has been demonstrated mainly through a paracrine effect …

Erectile dysfunction and exosome therapy

H Feng, W Peng, Z Deng, J Liu, T Wang - Frontiers in Endocrinology, 2023 - frontiersin.org
Erectile dysfunction (ED), as a common male disease, can seriously reduce the life quality of
men and their partners. With the improvement of human living standards, ED is considered …

Mesenchymal stem cell‐derived exosomes ameliorate erection by reducing oxidative stress damage of corpus cavernosum in a rat model of artery injury

Y Liu, S Zhao, L Luo, J Wang, Z Zhu… - Journal of Cellular …, 2019 - Wiley Online Library
Erectile dysfunction (ED) is a common ageing male's disease, and vascular ED accounts for
the largest proportion of all types of ED. One of the mechanisms of vascular ED in the clinic …

Exosomes derived from smooth muscle cells ameliorate diabetes‐induced erectile dysfunction by inhibiting fibrosis and modulating the NO/cGMP pathway

J Song, T Sun, Z Tang, Y Ruan, K Liu… - Journal of Cellular …, 2020 - Wiley Online Library
Erectile dysfunction (ED) is a major health issue among men with diabetes, and ED induced
by diabetes mellitus (DMED) is particularly difficult to treat. Therefore, novel therapeutic …

Exosomes derived from mesenchymal stem cells exert therapeutic effect in a rat model of cavernous nerves injury

M Li, H Lei, Y Xu, H Li, B Yang, C Yu, Y Yuan… - …, 2018 - Wiley Online Library
Postradical prostatectomy erectile dysfunction (pRP‐ED) is a major health issue. There has
been a shortage of an effective treatment method until now. In this study, a total of 48 adult …

Extracellular vesicles from human urine-derived stem cells ameliorate erectile dysfunction in a diabetic rat model by delivering proangiogenic microRNA

B Ouyang, Y Xie, C Zhang, C Deng, L Lv, J Yao… - Sexual …, 2019 - academic.oup.com
Introduction Stem cell therapies represent a promising new frontier for the treatment of
refractory diabetic erectile dysfunction (DED). The use of stem cell-derived extracellular …

Transplantation of adipose tissue‐derived stem cell‐derived exosomes ameliorates erectile function in diabetic rats

LL Zhu, X Huang, W Yu, H Chen, Y Chen, YT Dai - Andrologia, 2018 - Wiley Online Library
Mesenchymal stem cells (MSC s) have been considered as an attractive tool for the therapy
of diseases. Accumulating evidence indicates that the healing effects of MSC s are mainly …

Stem cell therapy for erectile dysfunction: a systematic review

TP Furtado, G Saffati, MH Furtado… - Sexual Medicine …, 2024 - academic.oup.com
Introduction Erectile dysfunction (ED) is a common condition that negatively affects men's
quality of life. It can have various causes, including psychological, vascular, and neurologic …