High concentrations of reactive oxygen and nitrogen species (RONS) are key characteristics
of inflammatory sites. Scavenging RONS at the site of inflammation is an effective …

Oxidative stress is associated with many acute and chronic inflammatory diseases, yet
limited treatment is currently available clinically. The development of enzyme-mimicking …

It is of great significance to eliminate excessive reactive oxygen species (ROS) for treating
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …

Colitis-associated colorectal cancer, which represents a highly aggressive subtypes of
colorectal cancer, requires concurrent antitumor and anti-inflammation therapies in clinic …

Inflammatory bowel disease (IBD) is an incurable disease of the gastrointestinal tract with a
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …

Inflammatory bowel disease (IBD) is a life-threatening organ dysfunction amplified by
complex interactions between genetic, environmental, and immune factors. Sulfasalazine …

The development of enzyme mimetics that clear excess mitochondrial reactive oxidative
stress (ROS) could provide effective treatment for a wide variety of diseases. Herein …

Ascorbate peroxidase (APX) as a crucial antioxidant enzyme has drawn attentions for its
utilization in preventing cells from oxidative stress responses by efficiently scavenging H2O2 …

Oxidative stress is a compelling risk factor in chronic kidney diseases and is further
aggravated for individuals during extracorporeal blood purification, ultimately leading to …

Nanozyme-mediated antioxidative therapy is a promising star for treating a myriad of
important diseases through eliminating excessive reactive oxygen species (ROS) such as …