Providing donor specific tolerance and avowing the adverse effects of systemic
immunosuppression is the ultimate aim of vascularized composite allotransplantation …

The immunology of composite tissue allotransplantation is complex because the grafts are
composed of a variety of tissues, such as skin, fat, muscle, nerves, lymph nodes, bone …

Cellular and vascularized bone marrow cells have been used to induce donor‐specific
chimerism in various models of composite tissue allotransplantation. Although thymus …

Background: Vascularized composite allotransplantation is constrained by complications
associated with standard immunosuppressive strategies. Vascularized thymus and bone …

Advanced microsurgical techniques have allowed performing different composite tissue
allotransplantations (CTA), although immunology and pharmacotherapy still have many …

Composite tissue allotransplants (CTA) involves transplantation of various tissues including
vessels, nerves, skin, and immune cells and bears significant antigenic load. Different …

It is important to understand the mechanisms of bone marrow based allograft tolerance
induction to explain the diverse variables controlling the subsequent outcome of the solid …

Results: The presence of DSC was evaluated in donor T, B, and monocyte/granulocyte/
dendritic cells (MGDC) in both groups. Chimerism levels (CL) at the end-point of the …

Vascularized bone marrow transplant (VBMT) induces donor-specific chimerism in
experimental models across the major histocompatibility barrier. An experimental model for …

Vascularized bone marrow transplant (VBMT) induces donor-specific chimerism in
experimental models across the major histocompatibility barrier. An experimental model for …