Naive CD4+ T cells can differentiate into different cell subsets after receiving antigen
stimulation, which secrete corresponding characteristic cytokines and thereby exert …

T helper 22 (Th22) cells, a newly defined CD4+ T-cell lineage, are characterized by their
distinct cytokine profile, which primarily consists of IL-13, IL-22 and TNF-α. Th22 cells …

Upon antigenic stimulation, naïve CD4+ T cells differentiate into different subsets and
secrete various cytokines to exert biological effects. Th22 cells, a newly identified CD4+ T …

T helper (Th) cells develop from naïve CD4+ T cells under lineage-specific culture
conditions and are nominated by their lineage-specific cytokines. Th22 cells, new players in …

Abstract T helper cell 22 (Th22) is a new subset of T cells clearly separate from Th17 and
other known T cell subsets with distinct gene expression and function. With the CCR6+ …

Th22 cells are a major source of IL-22 and have been found at sites of infection and in a
range of inflammatory diseases. However, their molecular characteristics and functional …

The helper T cell 9 (Thelper-9, Th9), as a functional subgroup of CD4+ T cells, was first
discovered in 2008. Th9 cells expressed transcription factor PU. 1 and cytokine interleukin-9 …

Upon activation, naive CD4+ T cells differentiate into different lineages of effector Th
subsets. Each subset is characterized by its unique cytokine profile and biological functions …

CD4+ T cells, upon activation and expansion, develop into different T helper cell subsets
with different cytokine profiles and distinct effector functions. Until recently, T cells were …

In the few years since their discovery, T helper 17 cells (TH 17) have been shown to play an
important role in host defense against infections, and in tissue inflammation during …