Molecular mechanisms of mesenchymal stem cell-based therapy in acute kidney injury

PW Lee, BS Wu, CY Yang, OKS Lee - International journal of molecular …, 2021 - mdpi.com
Acute kidney injury (AKI) causes a lot of harm to human health but is treated by only
supportive therapy in most cases. Recent evidence shows that mesenchymal stem cells …

Regenerative abilities of mesenchymal stem cells via acting as an ideal vehicle for subcellular component delivery in acute kidney injury

L Zhao, C Hu, F Han, J Wang… - Journal of cellular and …, 2020 - Wiley Online Library
Cell‐to‐cell communication and information exchange is one of the most important events in
multiple physiological processes, including multicellular organism development, cellular …

[HTML][HTML] Potential advantages of acute kidney injury management by mesenchymal stem cells

F Bianchi, E Sala, C Donadei, I Capelli… - World Journal of Stem …, 2014 - ncbi.nlm.nih.gov
Mesenchymal stem cells are currently considered as a promising tool for therapeutic
application in acute kidney injury (AKI) management. AKI is characterized by acute tubular …

[HTML][HTML] The beneficial effects of mesenchymal stem cells in acute kidney injury: A narrative review

Y Liu, J Han, J Fang, R Li - Current Stem Cell Research & Therapy, 2023 - ncbi.nlm.nih.gov
Background: Acute kidney injury (AKI) is a multifaced disease characterized by a rapid
decline in renal function. However, with growing insight into the pathophysiologic …

[HTML][HTML] In search of mechanisms associated with mesenchymal stem cell-based therapies for acute kidney injury

DC de Almeida, C Donizetti-Oliveira… - The Clinical …, 2013 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is classically described as a rapid loss of kidney function. AKI
affects more than 15% of all hospital admissions and is associated with elevated mortality …

Mesenchymal stem cell-derived extracellular vesicles to the rescue of renal injury

L Birtwistle, XM Chen, C Pollock - International Journal of Molecular …, 2021 - mdpi.com
Acute kidney injury (AKI) and chronic kidney disease (CKD) are rising in global prevalence
and cause significant morbidity for patients. Current treatments are limited to slowing instead …

Mesenchymal stem cells in acute kidney injury

BD Humphreys, JV Bonventre - Annu. Rev. Med., 2008 - annualreviews.org
The potential role of mesenchymal stem cells (MSCs, also called mesenchymal stromal
cells) in endogenous repair and cell-based therapies for acute kidney injury (AKI) is under …

Therapeutic action of bone marrow-derived stem cells against acute kidney injury

P Liu, Y Feng, Y Wang, Y Zhou - Life Sciences, 2014 - Elsevier
Acute kidney injury (AKI) is a frequent clinical disease with a high morbidity rate and
mortality rate, while the treatment options for this intractable disease are limited currently. In …

Mesenchymal stem cells and extracellular vesicles in therapy against kidney diseases

Y Huang, L Yang - Stem cell research & therapy, 2021 - Springer
Kidney diseases pose a threat to human health due to their rising incidence and fatality rate.
In preclinical and clinical studies, it has been acknowledged that mesenchymal stem cells …

Mesenchymal stem cell-derived extracellular vesicles: a potential therapeutic strategy for acute kidney injury

JK Li, C Yang, Y Su, JC Luo, MH Luo… - Frontiers in …, 2021 - frontiersin.org
Acute kidney injury (AKI) is a common and potential life-threatening disease in patients
admitted to hospital, affecting 10%–15% of all hospitalizations and around 50% of patients …