Nutraceutical approach to chronic osteoarthritis: from molecular research to clinical evidence
A Colletti, AFG Cicero - International journal of molecular sciences, 2021 - mdpi.com
Osteoarthritis (OA) is a degenerative inflammatory condition of the joint cartilage that
currently affects approximately 58 million adults in the world. It is characterized by pain …
currently affects approximately 58 million adults in the world. It is characterized by pain …
Nutraceuticals: potential for chondroprotection and molecular targeting of osteoarthritis
DJ Leong, M Choudhury, DM Hirsh, JA Hardin… - International journal of …, 2013 - mdpi.com
Osteoarthritis (OA) is a degenerative joint disease and a leading cause of adult disability.
There is no cure for OA, and no effective treatments which arrest or slow its progression …
There is no cure for OA, and no effective treatments which arrest or slow its progression …
Nutraceutical supplements in the management and prevention of osteoarthritis
P Castrogiovanni, FM Trovato, C Loreto, H Nsir… - International journal of …, 2016 - mdpi.com
Nutraceuticals are dietary compounds which have a role in the balance of anabolic and
catabolic signals in joints. Their regulatory function on homeostasis of cartilage metabolism …
catabolic signals in joints. Their regulatory function on homeostasis of cartilage metabolism …
Nutraceutical activity in osteoarthritis biology: a focus on the nutrigenomic role
S D'Adamo, S Cetrullo, V Panichi, E Mariani… - Cells, 2020 - mdpi.com
Osteoarthritis (OA) is a disease associated to age or conditions that precipitate aging of
articular cartilage, a post-mitotic tissue that remains functional until the failure of major …
articular cartilage, a post-mitotic tissue that remains functional until the failure of major …
Emerging trend in the pharmacotherapy of osteoarthritis
W Zhang, WB Robertson, J Zhao, W Chen… - Frontiers in …, 2019 - frontiersin.org
Osteoarthritis (OA) is a degenerative joint disorder and one of the most prevalent diseases
among the elderly population. Due to the limited spontaneous healing capacity of articular …
among the elderly population. Due to the limited spontaneous healing capacity of articular …
Therapeutics in osteoarthritis based on an understanding of its molecular pathogenesis
JR Kim, JJ Yoo, HA Kim - International journal of molecular sciences, 2018 - mdpi.com
Osteoarthritis (OA) is the most prevalent joint disease in older people and is characterized
by the progressive destruction of articular cartilage, synovial inflammation, changes in …
by the progressive destruction of articular cartilage, synovial inflammation, changes in …
Fundamentals of osteoarthritis: Inflammatory mediators in osteoarthritis
A De Roover, A Escribano-Núñez… - Osteoarthritis and …, 2023 - Elsevier
Objectives As more has become known of the pathophysiology of osteoarthritis (OA),
evidence that inflammation plays a critical role in its development and progression has …
evidence that inflammation plays a critical role in its development and progression has …
Role of physical exercise and nutraceuticals in modulating molecular pathways of osteoarthritis
A de Sire, N Marotta, C Marinaro, C Curci… - International Journal of …, 2021 - mdpi.com
Osteoarthritis (OA) is a painful and disabling disease that affects millions of patients. Its
etiology is largely unknown, but it is most likely multifactorial. OA pathogenesis involves the …
etiology is largely unknown, but it is most likely multifactorial. OA pathogenesis involves the …
Emerging pharmaceutical therapeutics and delivery technologies for osteoarthritis therapy
CY Shentu, G Yan, DC Xu, Y Chen… - Frontiers in …, 2022 - frontiersin.org
Osteoarthritis (OA) is one of the most common joint degenerative diseases in the world. At
present, the management of OA depends on the lifestyle modification and joint replacement …
present, the management of OA depends on the lifestyle modification and joint replacement …
Emerging targets in osteoarthritis therapy
MB Goldring, F Berenbaum - Current opinion in pharmacology, 2015 - Elsevier
Highlights•Different OA etiologies present a challenge for developing a single targeted
therapy.•Common mechanisms occur in inflammatory, mechanical, and oxidative stress in …
therapy.•Common mechanisms occur in inflammatory, mechanical, and oxidative stress in …