Osteoarthritis (OA) is a degenerative inflammatory condition of the joint cartilage that
currently affects approximately 58 million adults in the world. It is characterized by pain …

Osteoarthritis (OA) is a degenerative joint disease and a leading cause of adult disability.
There is no cure for OA, and no effective treatments which arrest or slow its progression …

Nutraceuticals are dietary compounds which have a role in the balance of anabolic and
catabolic signals in joints. Their regulatory function on homeostasis of cartilage metabolism …

Osteoarthritis (OA) is a disease associated to age or conditions that precipitate aging of
articular cartilage, a post-mitotic tissue that remains functional until the failure of major …

Osteoarthritis (OA) is a degenerative joint disorder and one of the most prevalent diseases
among the elderly population. Due to the limited spontaneous healing capacity of articular …

Osteoarthritis (OA) is the most prevalent joint disease in older people and is characterized
by the progressive destruction of articular cartilage, synovial inflammation, changes in …

Objectives As more has become known of the pathophysiology of osteoarthritis (OA),
evidence that inflammation plays a critical role in its development and progression has …

Osteoarthritis (OA) is a painful and disabling disease that affects millions of patients. Its
etiology is largely unknown, but it is most likely multifactorial. OA pathogenesis involves the …

Osteoarthritis (OA) is one of the most common joint degenerative diseases in the world. At
present, the management of OA depends on the lifestyle modification and joint replacement …

Highlights•Different OA etiologies present a challenge for developing a single targeted
therapy.•Common mechanisms occur in inflammatory, mechanical, and oxidative stress in …