Women and men can differ in their propensity to take risks and develop impulse control and
addiction disorders. Sexual dimorphisms in behavioral control by the mesolimbic …

Deficits in cost/benefit decision making is a critical risk factor for gambling disorder. Reward‐
paired cues may play an important role, as these stimuli can enhance risk preference in rats …

Many debilitating psychiatric conditions, including drug addiction, are characterized by poor
decision making and maladaptive risk-taking. Recent research has begun to probe this …

The nucleus accumbens, a site within the ventral striatum, plays a prominent role in
mediating the reinforcing effects of drugs of abuse, food, sex, and other addictions. Indeed, it …

Anabolic-androgenic steroid (AAS) abuse is implicated in maladaptive decision making
such as increased risk taking and problem gambling. Endogenous testosterone correlates …

Hormonal contraceptives (HCs) containing synthetic ovarian hormones are commonly used
among reproductive aged women; HCs alter the physiological state of the user by interfering …

Background Both psychostimulant use and engagement with probabilistic schedules of
reward sensitize the mesocorticolimbic dopamine (DA) system. Such behaviors may act …

Experience with sexual behavior causes cross-sensitization of amphetamine reward, an
effect dependent on a period of sexual reward abstinence. We previously showed that …

Similar to other addiction disorders, the cues inherent in many gambling procedures are
thought to play an important role in mediating their addictive nature. Animal models of …

Sex differences in behavioural patterns of drug abuse and dependence have been
hypothesized to be a consequence of sexual dimorphisms in brain pathways, particularly …