Availability of artificial light and light-emitting devices have altered human temporal life,
allowing 24-hour healthcare, commerce and production, and expanding social life around …

Most organisms display endogenously produced∼ 24-hour fluctuations in physiology and
behavior, termed circadian rhythms. Circadian rhythms are driven by a transcriptional …

Life on earth has evolved during the past several billion years under relatively bright days
and dark night conditions. The wide-spread adoption of electric lights during the past century …

Circadian disruption is pervasive and can occur at multiple organizational levels,
contributing to poor health outcomes at individual and population levels. Evidence points to …

Circadian rhythms are generated by the circadian clock, a self-sustained internal timing
system that exhibits 24-h rhythms in the body. In mammals, circadian rhythms are driven by …

Simple Summary Our daily life follows 24-h cycles in various biological functions, such as
sleep–wake and feeding/fasting cycles. These rhythms are regulated by endogenous clocks …

Abstract Circadian (∼ 24-hour) timing systems pervade all kingdoms of life and temporally
optimize behavior and physiology in humans. Relatively recent changes to our …

Circadian rhythms are generated by the autonomous circadian clock, the suprachiasmatic
nucleus (SCN), and clock genes that are present in all tissues. The SCN times these …

With the exception of high latitudes, life has evolved under bright days and dark nights. Most
organisms have developed endogenously driven circadian rhythms that are synchronized to …

The disruption of circadian rhythms by environmental conditions can induce alterations in
body homeostasis, from behavior to metabolism. The light: dark cycle is the most reliable …