[HTML][HTML] Co-prescription of dual-antiplatelet therapy and proton pump inhibitors: current guidelines

H Saven, L Zhong, IM McFarlane - Cureus, 2022 - ncbi.nlm.nih.gov
Dual-antiplatelet therapy (DAPT) prevents thrombotic complications associated with
coronary artery disease, acute coronary syndrome, and stent thrombosis following the …

Analysis of gastrointestinal prophylaxis in patients receiving dual antiplatelet therapy with aspirin and clopidogrel

KM Morneau, AB Reaves, JB Martin… - Journal of Managed Care …, 2014 - jmcp.org
BACKGROUND: Dual antiplatelet therapy (DAPT) has been found to reduce the risk of
cardiac death, myocardial infarction, stroke, and stent thrombosis following acute coronary …

[HTML][HTML] The Efficacy and Safety of Proton Pump Inhibitors Combining Dual Antiplatelet Therapy in Patients with Coronary Intervention: A Systematic Review, Meta …

S Liang, M Ma, Y Chen, J Zhang, J Li… - Reviews in …, 2023 - imrpress.com
Background: Proton pump inhibitors (PPIs) are used to prevent gastrointestinal hemorrhage
in patients with coronary treatment undergoing dual antiplatelet therapy (DAPT). Methods: A …

[HTML][HTML] Clinical outcomes of concomitant use of proton pump inhibitors and dual antiplatelet therapy: a systematic review and meta-analysis

H Guo, Z Ye, R Huang - Frontiers in Pharmacology, 2021 - frontiersin.org
Background: The safety and efficacy associated with the use of proton pump inhibitors (PPIs)
by patients with coronary artery disease receiving dual antiplatelet therapy (DAPT) remain …

Randomized clinical trial: the impact of gastrointestinal risk factor screening and prophylactic proton pump inhibitor therapy in patients receiving dual antiplatelet …

BES Jensen, JM Hansen, KS Larsen… - European Journal of …, 2017 - journals.lww.com
Objective Dual antiplatelet therapy reduces the risk of ischemic complications after acute
coronary syndrome, but increases the risk of bleeding including upper gastrointestinal …

Reduced risk of gastrointestinal bleeding associated with proton pump inhibitor therapy in patients treated with dual antiplatelet therapy after myocardial infarction

TSG Sehested, N Carlson, PW Hansen… - European Heart …, 2019 - academic.oup.com
Aims Guidelines differ in their recommendations on therapy to prevent gastrointestinal
bleeding for patients treated with dual antiplatelet treatment (DAPT). We sought to …

Systematic review and meta-analysis: the effects of prophylactic proton pump inhibitor treatment in patients with coronary heart disease receiving dual antiplatelet …

Y Li, X Ren, Z Fang - Journal of Cardiovascular Pharmacology, 2021 - journals.lww.com
Dual antiplatelet therapy (DAPT) and proton pump inhibitors (PPIs) are widely used in
clinical treatment. However, the pharmacokinetic interaction between PPIs and DAPT is still …

[HTML][HTML] Proton pump inhibitor in the prevention of upper gastrointestinal mucosal injury associated with dual antiplatelet therapy after coronary artery bypass grafting …

Y Zhu, X Wang, Y Yang, L Liu, Q Zhao, L Yu - Trials, 2022 - Springer
Background Dual antiplatelet therapy (DAPT) is recommended in secondary prevention after
coronary artery bypass grafting (CABG), but it is inevitably associated with the risk of …

Impact of proton pump inhibitors and dual antiplatelet therapy cessation on outcomes following percutaneous coronary intervention: Results From the PARIS Registry

J Chandrasekhar, S Bansilal, U Baber… - Catheterization and …, 2017 - Wiley Online Library
Background Proton pump inhibitors (PPI) may decrease the availability of clopidogrel by
competitive antagonism, leading to a potential increase in ischemic events. Methods We …

H2 receptor antagonists versus proton pump inhibitors in patients on dual antiplatelet therapy for coronary artery disease: a systematic review

A Almufleh, FD Ramirez, D So, M Le May, AY Chong… - Cardiology, 2018 - karger.com
Objectives: Mitigating the gastrointestinal (GI) bleeding risks of dual antiplatelet therapy
(DAPT) is a common clinical concern. While proton pump inhibitors (PPIs) remain the most …