Background: Most studies that assess efficacy of antimalarial drugs focus on the outcome of
clinical treatment. However, community surveys of surrogate indicators are often more …

Abstract Background Point mutations in Plasmodium falciparum dihydrofolate reductase
(Pfdhfr) and dihydropteroate synthase (Pfdhps) genes which confer resistance to …

Background In late 2002, the health authorities of Mozambique implemented sulphadoxine-
pyrimethamine (SP)/amodiaquine (AQ) as first-line treatment against uncomplicated …

Estimation of the prevalence of the molecular markers of sulfadoxine/pyrimethamine (SP)
and chloroquine (CQ) resistance and validation of the association of mutations with …

Abstract Background In Benin, very few studies have been done on the genetics of
Plasmodium falciparum and the resistance markers of anti-malarial drugs, while malaria …

Background Malaria is a major parasitic disease, affecting millions of people in endemic
areas. Plasmodium falciparum parasites are responsible for the most severe cases and its …

The archipelago of the Democratic Republic (Loureiro et al., 1996). In addition to socio–
economic impediments, the inadequate use of Sao Tomé and Prõncipe (DRSTP) is located …

Markers of Plasmodium falciparum resistance to chloroquine (CQ) and pyrimethamine-
sulfadoxine (PYR-SDX) are widespread in areas where malaria is endemic. In an area …

Background The malaria situation has been worsening in Angola, partly due to armed
conflict until the recent past and drug-resistant Plasmodium falciparum. Malaria transmission …

Background Understanding the geographical distribution of drug resistance of Plasmodium
falciparum is important for the effective treatment of malaria. Drug resistance has previously …