[HTML][HTML] Glioblastoma targeted therapy: updated approaches from recent biological insights
Glioblastoma (WHO grade IV astrocytoma) is the most frequent primary brain tumor in adults,
representing a highly heterogeneous group of neoplasms that are among the most …
representing a highly heterogeneous group of neoplasms that are among the most …
Emerging therapies for glioblastoma: current state and future directions
L Rong, N Li, Z Zhang - Journal of Experimental & Clinical Cancer …, 2022 - Springer
Glioblastoma (GBM) is the most common high-grade primary malignant brain tumor with an
extremely poor prognosis. Given the poor survival with currently approved treatments for …
extremely poor prognosis. Given the poor survival with currently approved treatments for …
New approaches to glioblastoma
M Khasraw, Y Fujita, C Lee-Chang… - Annual review of …, 2022 - annualreviews.org
Faced with unique immunobiology and marked heterogeneity, treatment strategies for
glioblastoma require therapeutic approaches that diverge from conventional oncological …
glioblastoma require therapeutic approaches that diverge from conventional oncological …
Glioma targeted therapy: insight into future of molecular approaches
Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically,
gliomas occur among all ages, more often seen in adults, which males are more susceptible …
gliomas occur among all ages, more often seen in adults, which males are more susceptible …
Diagnostic and therapeutic avenues for glioblastoma: no longer a dead end?
S Tanaka, DN Louis, WT Curry, TT Batchelor… - Nature reviews Clinical …, 2013 - nature.com
Glioblastomas are heterogeneous neoplasms that are driven by complex signalling
pathways, and are among the most aggressive and challenging cancers to treat. Despite …
pathways, and are among the most aggressive and challenging cancers to treat. Despite …
[HTML][HTML] Development of targeted therapies in treatment of glioblastoma
YY Xu, P Gao, Y Sun, YR Duan - Cancer biology & medicine, 2015 - ncbi.nlm.nih.gov
Glioblastoma (GBM) is a type of tumor that is highly lethal despite maximal therapy.
Standard therapeutic approaches provide modest improvement in progression-free and …
Standard therapeutic approaches provide modest improvement in progression-free and …
From signalling pathways to targeted therapies: unravelling glioblastoma's secrets and harnessing two decades of progress
Glioblastoma, a rare, and highly lethal form of brain cancer, poses significant challenges in
terms of therapeutic resistance, and poor survival rates for both adult and paediatric patients …
terms of therapeutic resistance, and poor survival rates for both adult and paediatric patients …
Management of glioblastoma: State of the art and future directions
Glioblastoma is the most common malignant primary brain tumor. Overall, the prognosis for
patients with this disease is poor, with a median survival of< 2 years. There is a slight …
patients with this disease is poor, with a median survival of< 2 years. There is a slight …
The challenges associated with molecular targeted therapies for glioblastoma
TR Jue, KL McDonald - Journal of Neuro-Oncology, 2016 - Springer
Glioblastoma (GBM) is the most aggressive malignant brain tumor in adults. Improvements
in the treatment of GBM have remained static since the advent of the standard therapy which …
in the treatment of GBM have remained static since the advent of the standard therapy which …
Current challenges and opportunities in treating glioblastoma
A Shergalis, A Bankhead, U Luesakul… - Pharmacological …, 2018 - ASPET
Glioblastoma multiforme (GBM), the most common and aggressive primary brain tumor, has
a high mortality rate despite extensive efforts to develop new treatments. GBM exhibits both …
a high mortality rate despite extensive efforts to develop new treatments. GBM exhibits both …