Potential roles of selectins in periodontal diseases and associated systemic diseases: could they be targets for immunotherapy?
M Zhong, J Huang, Z Wu, KG Chan, L Wang… - International Journal of …, 2022 - mdpi.com
Periodontal diseases are predisposing factors to the development of many systemic
disorders, which is often initiated via leukocyte infiltration and vascular inflammation. These …
disorders, which is often initiated via leukocyte infiltration and vascular inflammation. These …
Immunological insights of selectins in human disease mechanism
Selectin enzymes are glycoproteins and are an important adhesion molecule in the
mammalian immune system, especially in the inflammatory response and the healing …
mammalian immune system, especially in the inflammatory response and the healing …
Selectin-mediated leukocyte trafficking during the development of autoimmune disease
S Angiari - Autoimmunity reviews, 2015 - Elsevier
Tissue inflammation is a finely regulated process that controls wound healing and allows the
clearance of damaged cells, pathogens and irritants. However, excessive or uncontrolled …
clearance of damaged cells, pathogens and irritants. However, excessive or uncontrolled …
Selectins—an emerging target for drug delivery
C Ehrhardt, C Kneuer, U Bakowsky - Advanced drug delivery reviews, 2004 - Elsevier
Selectins are multifunctional adhesion molecules that mediate the initial interactions
between circulating leukocytes and cells of the endothelium. First identified over a decade …
between circulating leukocytes and cells of the endothelium. First identified over a decade …
Selectins: critical mediators of leukocyte recruitment
KD Patel, SL Cuvelier, S Wiehler - Seminars in immunology, 2002 - Elsevier
Selectins are multi-functional adhesion molecules that mediate the initial interactions
between circulating leukocytes and the endothelium. First identified over a decade ago …
between circulating leukocytes and the endothelium. First identified over a decade ago …
Modulation of P-selection and platelet aggregation in chronic periodontitis: a clinical study
R Perumal, M Rajendran… - Journal of Indian …, 2014 - journals.lww.com
Background: The primary etiologic factor of periodontitis is the subgingival infection with a
group of Gram negative pathogens. Transient bacteremia in periodontitis patients underlie …
group of Gram negative pathogens. Transient bacteremia in periodontitis patients underlie …
Periodontopathogens induce soluble P-selectin release by endothelial cells and platelets
A Assinger, E Buchberger, M Laky, A Esfandeyari… - Thrombosis research, 2011 - Elsevier
INTRODUCTION: Soluble P-selectin plays a pivotal role in inflammation and the
development of thrombotic and cardiovascular disease. Accordingly, elevated levels of …
development of thrombotic and cardiovascular disease. Accordingly, elevated levels of …
Inhibitors of selectin functions in the treatment of inflammatory skin disorders
MP Schön - Therapeutics and Clinical Risk Management, 2005 - Taylor & Francis
Selectins mediate tethering and rolling of leukocytes to the vascular endothelium, the first
adhesive step in the recruitment of immune cells to inflamed tissues. Thus, selectins play a …
adhesive step in the recruitment of immune cells to inflamed tissues. Thus, selectins play a …
Influence of sE‐selectin and L‐selectin on the regulation of cell migration during chronic periodontitis
W Krugluger, A Nell, P Solar, M Matejka… - Journal of …, 1995 - Wiley Online Library
Soluble endothelial leukocyte adhesion molecule‐1 (sE‐selectin) levels in peripheral blood
(PB) and gingival capillary blood (GCB) of both healthy donors (HD) and patients with adult …
(PB) and gingival capillary blood (GCB) of both healthy donors (HD) and patients with adult …
Selectins and their ligands as potential immunotherapeutic targets in neurological diseases
S Angiari, G Constantin - Immunotherapy, 2013 - Taylor & Francis
Selectins are a family of adhesion receptors that bind to highly glycosylated molecules
expressed on the surface of leukocytes and endothelial cells. The interactions between …
expressed on the surface of leukocytes and endothelial cells. The interactions between …