Galectin 3 is a member of a family of β-galactoside binding proteins and has emerged as an
important regulator of diverse functions critical in cancer biology including apoptosis …

Galectin-3 is a mammalian β-galactoside-binding protein that is expressed by various types
of human cells. Changes in galectin-3 expression and subcellular and intercellular …

The relationship between a tumor cell and its microenvironment is bi-directional. The
proteins expressed by the tumor cells alter the signatures on the seemingly normal stromal …

The microenvironment of a tumor is a highly complex milieu, primarily characterized by
immunosuppression, abnormal angiogenesis, and hypoxic regions. These features promote …

Galectin-3 is a pleiotropic carbohydrate-binding protein involved in a variety of normal and
pathological biological processes. Its carbohydrate-binding properties constitute the basis …

Interactions between two cells or between cell and extracellular matrix mediated by protein–
carbohydrate interactions play pivotal roles in modulating various biological processes such …

Galectin-3, the only chimera galectin found in vertebrates, is one of the best-studied
galectins. It is expressed in several cell types and is involved in a broad range of …

Galectin‐3 is a carbohydrate‐binding protein endowed with affinity for β‐galactosides. It
plays a role in cell–cell and cell–matrix interactions. Furthermore, it has been hypothesized …

Galectins are a family of structurally related carbohydrate-binding proteins, which are
defined by their affinity for poly-N-acetyllactosamine-enriched glycoconjugates and …

Galectin family members have been shown to exert multiple roles in the context of tumor
biology. Several recent findings support a similar multi-faceted role for galectin-9. Galectin-9 …