NorA is the best studied efflux system of Staphylococcus aureus and therefore frequently
used as a model for investigating efflux-mediated resistance in this pathogen. NorA activity …

The norA gene, which is located on the chromosome of Staphylococcus aureus, encodes
the multidrug efflux protein with 12 transmembrane segments (TMS), and the …

Staphylococcus aureus strains harboring QacA, QacB, QacC, QacG transporters and norA
promoter up-regulating mutations were characterized by phenotype microarray (PM) …

Background Efflux of antibiotics is an effective resistance mechanism among antibiotic-
resistant Staphylococcus aureus. This systematic review aims to evaluate the frequency and …

NorA, a multidrug efflux pump in Staphylococcus aureus, protects the cell from multiple
drugs, including quinolones. The flqB mutation (T→ G) in the 5′ untranslated region …

The intensively intermittent use of antibiotics promotes the rapid evolution of tolerance,
which may lead to resistance acquisition in the following evolutionary trajectory. In addition …

Transport processes are used by all organisms to obtain essential nutrients and to expel
wastes and other potentially harmful substances from cells. Such processes are important …

NorA is a Staphylococcus aureus multidrug transporter that confers resistance to structurally
distinct compounds. The MgrA global regulatory protein is reported to augment norA …

Staphylococcus aureus utilizes efflux transporter NorA to pump out a wide range of
structurally dissimilar drugs, conferring low-level multidrug resistance. The regulation of …

Staphylococcus aureus has acquired resistance to antibiotics since their first use. The S.
aureus protein NorA, an efflux pump belonging to the major facilitator superfamily (MFS) …