[HTML][HTML] Normal and pathological erythropoiesis in adults: from gene regulation to targeted treatment concepts

P Valent, G Büsche, I Theurl, IZ Uras, U Germing… - …, 2018 - ncbi.nlm.nih.gov
Pathological erythropoiesis with consequent anemia is a leading cause of symptomatic
morbidity in internal medicine. The etiologies of anemia are complex and include reactive as …

Erythropoiesis: insights into pathophysiology and treatments in 2017

A Zivot, JM Lipton, A Narla, L Blanc - Molecular Medicine, 2018 - Springer
Erythropoiesis is a tightly-regulated and complex process originating in the bone marrow
from a multipotent stem cell and terminating in a mature, enucleated erythrocyte. Altered red …

Erythroleukemia-historical perspectives and recent advances in diagnosis and management

P Boddu, CB Benton, W Wang, G Borthakur, JD Khoury… - Blood reviews, 2018 - Elsevier
Acute erythroleukemia is a rare form of acute myeloid leukemia recognized by its distinct
phenotypic attribute of erythroblastic proliferation. After a century of its descriptive history …

Comprehensive phenotyping of erythropoiesis in human bone marrow: evaluation of normal and ineffective erythropoiesis

H Yan, A Ali, L Blanc, A Narla, JM Lane… - American journal of …, 2021 - Wiley Online Library
Identification of stage‐specific erythroid cells is critical for studies of normal and disordered
human erythropoiesis. While immunophenotypic strategies have previously been developed …

Setting fire to ESA and EMA resistance: new targeted treatment options in lower risk myelodysplastic syndromes

AS Kubasch, U Platzbecker - International Journal of Molecular Sciences, 2019 - mdpi.com
During the last decade, substantial advances have been made in the understanding of the
complex molecular, immunological and cellular disturbances involved in the initiation as …

[HTML][HTML] Epigenetic and transcriptional control of erythropoiesis

M Wells, L Steiner - Frontiers in Genetics, 2022 - frontiersin.org
Erythropoiesis is a process of enormous magnitude, with the average person generating two
to three million red cells every second. Erythroid progenitors start as large cells with large …

Erythropoiesis stimulating agents and other growth factors in low-risk MDS

E Hellström-Lindberg, A van de Loosdrecht - Best practice & research …, 2013 - Elsevier
Anemia and transfusion need constitute major problems for patients with myelodysplastic
syndromes (MDS) and are associated with reduced quality of life, poorer survival and an …

Gene expression during terminal erythroid differentiation

PA Ney - Current opinion in hematology, 2006 - journals.lww.com
Gene expression during terminal erythroid differentiation : Current Opinion in Hematology Gene
expression during terminal erythroid differentiation : Current Opinion in Hematology Log in or …

Characterization, regulation, and targeting of erythroid progenitors in normal and disordered human erythropoiesis

BM Dulmovits, J Hom, A Narla… - Current opinion in …, 2017 - journals.lww.com
Characterization, regulation, and targeting of erythroid pro... : Current Opinion in
Hematology Characterization, regulation, and targeting of erythroid progenitors in normal …

Ineffective erythropoiesis and its treatment

M Cazzola - Blood, The Journal of the American Society of …, 2022 - ashpublications.org
The erythroid marrow and circulating red blood cells (RBCs) are the key components of the
human erythron. Abnormalities of the erythron that are responsible for anemia can be …