Many neurodegenerative diseases are characterized by abnormal protein aggregates,
including the two most common neurodegenerative diseases Alzheimer's disease (AD) and …

Increasing evidence indicates that lipid metabolism is disturbed in central nervous system
(CNS) disorders, such as multiple sclerosis, Alzheimer's, and Parkinson's disease …

The maintenance of lipid homeostasis is essential for the normal functioning of living
organisms. Alterations of the lipid homeostasis system remodel the composition of the …

Protein misfolding and accumulation defines a prevailing feature of many
neurodegenerative disorders, finally resulting in the formation of toxic intra-and extracellular …

Alzheimer's Diseases (AD) is characterized by the accumulation of amyloid deposits of Aβ
peptide in the brain. Besides genetic background, the presence of other diseases and an …

There are a vast number of neurodegenerative diseases, including Alzheimer's disease
(AD), Parkinson's disease (PD), and Huntington's disease (HD), associated with the …

More than a century has passed since pathological protein aggregates were first identified in
the brains of patients with neurodegenerative diseases (NDDs). Yet, we still do not have …

Lipid rafts are membrane microdomains, enriched in cholesterol and sphingolipids, into
which specific subsets of proteins and lipids partition, creating cell‐signalling platforms that …

Protein aggregation diseases involve intracellular accumulation or extracellular deposition
of certain protein species in neuronal or glial cells, leading to neurodegeneration and …

Lipids constitute the bulk of the dry mass of the brain and have been associated with healthy
function as well as the most common pathological conditions of the brain. Demographic …