Study objective A place for clonidine has been suggested for many indications in
perioperative medicine. The aim of this systematic review and these meta-analyses is to …

BACKGROUND: Clonidine is an α2-adrenoceptor agonist, which has analgesic properties.
However, the analgesic efficacy of perioperative clonidine remains unclear. We, therefore …

The effect of adding clonidine to local anesthetics for nerve or plexus blocks remains
unclear. The authors searched for randomized placebo-controlled trials testing the impact of …

Clonidine is classified as an imidazoline and it is the prototypical alpha-2 receptor agonists.
It has been used for several years to treat hypertension. It has also been used,“off label”, for …

Background Clonidine may be used along with intrathecal morphine for single-dose
postoperative analgesia in adults. The efficacy of this is not clear. Methods A meta-analysis …

Background Marked activation of the sympathetic nervous system occurs during and after
noncardiac surgery. Low-dose clonidine, which blunts central sympathetic outflow, may …

Clonidine, an alpha-2 adrenergic receptor agonist, has well-established role in acute
perioperative pain management. However, recently it has found increasing use in chronic …

Administration of perioperative clonidine can reduce the risk of perioperative myocardial
ischemia and mortality in patients undergoing non-cardiac surgery. Perioperative clonidine …

Study Objective: Determine the hemodynamic consequences of intraoperative clonidine
during major abdominal surgery. Design: Prospective open trial. Setting: Teaching hospital …

Clonidine may have beneficial effects in patients undergoing major surgery. We enrolled
156 patients having elective CABG surgery in a double-blind, randomized trial. Patients …