[PDF][PDF] The Role of Inflammation, Telomere Length and Hippocampal Neurogenesis in the Aetiology and Treatment of Psychiatric Disorders
A Palmos - 2020 - kclpure.kcl.ac.uk
Psychiatric disorders such as major depressive disorder, bipolar disorder and schizophrenia
are a tremendous burden on society, globally accounting for more than 30% of years lived …
are a tremendous burden on society, globally accounting for more than 30% of years lived …
[HTML][HTML] Telomere length and human hippocampal neurogenesis
Short telomere length is a risk factor for age-related disease, but it is also associated with
reduced hippocampal volumes, age-related cognitive decline and psychiatric disorder risk …
reduced hippocampal volumes, age-related cognitive decline and psychiatric disorder risk …
[PDF][PDF] The genomic clock: exploring the relationship between telomere length and mental disorders
Y Jiang, ZQ Du, HH Zhu - Psychosom Med Res, 2023 - tmrjournals.com
In the realm of neurology and cellular aging, a compelling nexus is being drawn between
mental disorders and the intricate clockwork of our genetic machinery, specifically telomere …
mental disorders and the intricate clockwork of our genetic machinery, specifically telomere …
[HTML][HTML] Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder
Stress can be a predisposing factor to psychiatric disorders and has been associated with
decreased neurogenesis and reduced hippocampal volume especially in depression …
decreased neurogenesis and reduced hippocampal volume especially in depression …
Adult hippocampal neurogenesis in major depressive disorder and Alzheimer's disease
T Berger, H Lee, AH Young, D Aarsland… - Trends in molecular …, 2020 - cell.com
Depression and dementia are major public health problems. Major depressive disorder
(MDD) and Alzheimer's disease (AD) reciprocally elevate the risk for one another. No …
(MDD) and Alzheimer's disease (AD) reciprocally elevate the risk for one another. No …
Adult neurogenesis, mental health, and mental illness: hope or hype?
Psychiatric and neurologic disorders take an enormous toll on society. Alleviating the
devastating symptoms and consequences of neuropsychiatric disorders such as addiction …
devastating symptoms and consequences of neuropsychiatric disorders such as addiction …
[HTML][HTML] Immediate early genes anchor a biological pathway of proteins required for memory formation, long-term depression and risk for schizophrenia
KK Marballi, AL Gallitano - Frontiers in behavioral neuroscience, 2018 - frontiersin.org
While the causes of myriad medical and infectious illnesses have been identified, the
etiologies of neuropsychiatric illnesses remain elusive. This is due to two major obstacles …
etiologies of neuropsychiatric illnesses remain elusive. This is due to two major obstacles …
Why has adult hippocampal neurogenesis had so little impact on psychiatry?
KY Liu, R Howard - The British Journal of Psychiatry, 2018 - cambridge.org
Hippocampal neurogenesis continues throughout adult life and potentially plays a crucial
role in mood and cognitive disorders. We summarise the preclinical insights and potential …
role in mood and cognitive disorders. We summarise the preclinical insights and potential …
Mechanisms of action of telomere-related genes and telomere length-related proteins in relation to psychiatric disorders: A multi-method Mendelian Randomization …
J Shen, Y Feng, H Yan - Available at SSRN 4527773, 2023 - papers.ssrn.com
Background: Psychiatric disorders (PD) refer to disorders that affect individual thinking,
emotional regulation, and behavior. Notably, PD are associated with factors such as genes …
emotional regulation, and behavior. Notably, PD are associated with factors such as genes …
Adult neurogenesis and psychiatric disorders
Psychiatric disorders continue to be among the most challenging disorders to diagnose and
treat because there is no single genetic or anatomical locus that is causative for the disease …
treat because there is no single genetic or anatomical locus that is causative for the disease …
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