The function of melanotransferrin: a role in melanoma cell proliferation and tumorigenesis

LL Dunn, EO Sekyere, Y Suryo Rahmanto… - …, 2006 - academic.oup.com
Melanotransferrin (MTf) or melanoma tumor antigen p97 is an iron (Fe) binding transferrin
homolog expressed highly on melanomas and at lower levels on normal tissues. It has been …

Identification of distinct changes in gene expression after modulation of melanoma tumor antigen p97 (melanotransferrin) in multiple models in vitro and in vivo

Y Suryo Rahmanto, LL Dunn, DR Richardson - Carcinogenesis, 2007 - academic.oup.com
Melanoma tumor antigen p97 or melanotransferrin (MTf) is an iron (Fe)-binding protein with
high homology to serum transferrin. MTf is expressed at very low levels in normal tissues …

The melanoma tumor antigen, melanotransferrin (p97): a 25-year hallmark–from iron metabolism to tumorigenesis

Y Suryo Rahmanto, LL Dunn, DR Richardson - Oncogene, 2007 - nature.com
Melanotransferrin (MTf) or melanoma tumor antigen p97 is a transferrin (Tf) homolog that is
found predominantly bound to the cell membrane via a glycosyl phosphatidylinositol anchor …

Melanotransferrin induces human melanoma SK-Mel-28 cell invasion in vivo

Y Bertrand, M Demeule, J Michaud-Levesque… - Biochemical and …, 2007 - Elsevier
The expression of melanotransferrin (MTf), a membrane-bound glycoprotein highly
expressed in melanomas, is correlated with tumor vascularization and progression …

Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo

EO Sekyere, LL Dunn, YS Rahmanto, DR Richardson - Blood, 2006 - ashpublications.org
Melanotransferrin (MTf) or tumor antigen p97 is a transferrin homolog that binds one iron
(Fe) atom and has been suggested to play roles in a variety of processes, including Fe …

Examination of the distribution of the transferrin homologue, melanotransferrin (tumour antigen p97), in mouse and human

EO Sekyere, LL Dunn, DR Richardson - Biochimica et Biophysica Acta …, 2005 - Elsevier
Melanotransferrin (MTf) is a transferrin homologue initially identified in melanoma cells.
Serum transferrin (Tf) contains two iron (Fe)-binding sites and plays a vital role in Fe …

[HTML][HTML] The membrane-bound transferrin homologue melanotransferrin: roles other than iron transport?

E Sekyere, DR Richardson - FEBS letters, 2000 - Elsevier
Melanotransferrin (MTf) is a membrane-bound transferrin (Tf) homologue that is found at
high levels in melanoma cells. MTf has many characteristics in common with serum Tf and …

Inhibition of melanoma brain metastasis by targeting melanotransferrin at the cell surface

Y Rolland, M Demeule, L Fenart… - Pigment cell & …, 2009 - Wiley Online Library
Brain metastases are a common feature of malignant melanoma and are associated with
poor prognosis. Melanotransferrin (MTf), one of several antigens associated with the surface …

Pattern of melanotransferrin expression in human colorectal tissues: an immunohistochemical study on potential clinical application

K Duś-Szachniewicz, P Ostasiewicz… - Anticancer …, 2015 - ar.iiarjournals.org
Background: Our previous liquid chromatography-tandem mass spectrometry (LC-MS/MS)
study on colorectal cancer proteome resulted in identification of 10,000 differentially …

Level of melanotransferrin in tissue and sera serves as a prognostic marker of gastric cancer

K Sawaki, M Kanda, S Umeda, T Miwa… - Anticancer …, 2019 - ar.iiarjournals.org
Aim: The aim of the study was to identify novel biomarkers that are vital for improving
management of patients with gastric cancer (GC). Materials and Methods: An RNA …