Advancements in the blood–brain barrier penetrating nanoplatforms for brain related disease diagnostics and therapeutic applications
S Thangudu, FY Cheng, CH Su - Polymers, 2020 - mdpi.com
Noninvasive treatments to treat the brain-related disorders have been paying more
significant attention and it is an emerging topic. However, overcoming the blood brain barrier …
significant attention and it is an emerging topic. However, overcoming the blood brain barrier …
Overcoming blood–brain barrier transport: Advances in nanoparticle-based drug delivery strategies
The blood–brain barrier (BBB), a unique structure in the central nervous system (CNS),
protects the brain from bloodborne pathogens by its excellent barrier properties …
protects the brain from bloodborne pathogens by its excellent barrier properties …
Nanoparticle-based drug delivery systems: an inspiring therapeutic strategy for neurodegenerative diseases
L Duan, X Li, R Ji, Z Hao, M Kong, X Wen, F Guan… - Polymers, 2023 - mdpi.com
Neurodegenerative diseases are common, incurable neurological disorders with high
prevalence, and lead to memory, movement, language, and intelligence impairments …
prevalence, and lead to memory, movement, language, and intelligence impairments …
Strategies for transporting nanoparticles across the blood–brain barrier
The existence of blood–brain barrier (BBB) hampers the effective treatment of central
nervous system (CNS) diseases. Almost all macromolecular drugs and more than 98% of …
nervous system (CNS) diseases. Almost all macromolecular drugs and more than 98% of …
Targeted delivery of nano-therapeutics for major disorders of the central nervous system
Major central nervous system (CNS) disorders, including brain tumors, Alzheimer's disease,
Parkinson's disease, and stroke, are significant threats to human health. Although …
Parkinson's disease, and stroke, are significant threats to human health. Although …
An insight to brain targeting utilizing polymeric nanoparticles: effective treatment modalities for neurological disorders and brain tumor
The delivery of therapeutic molecules to the brain remains an unsolved problem to the
researchers due to the existence of the blood–brain barrier (BBB), which halts the entry of …
researchers due to the existence of the blood–brain barrier (BBB), which halts the entry of …
Strategies facilitating the permeation of nanoparticles through blood-brain barrier: An insight towards the development of brain-targeted drug delivery system
The blood-brain barrier (BBB) is a membrane barrier considered one of the most crucial
protective architectures in the central nervous system (CNS). Its presence acts as a hurdle …
protective architectures in the central nervous system (CNS). Its presence acts as a hurdle …
Nanobiotechnology-based strategies for crossing the blood–brain barrier
KK Jain - Nanomedicine, 2012 - Taylor & Francis
The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it
also significantly hinders the delivery of therapeutics to the brain. Several strategies have …
also significantly hinders the delivery of therapeutics to the brain. Several strategies have …
Drug delivery to the brain across the blood–brain barrier using nanomaterials
A major obstacle facing brain diseases such as Alzheimer's disease, multiple sclerosis,
brain tumors, and strokes is the blood–brain barrier (BBB). The BBB prevents the passage of …
brain tumors, and strokes is the blood–brain barrier (BBB). The BBB prevents the passage of …
Challenges in drug delivery to the brain: nature is against us
S Krol - Journal of Controlled Release, 2012 - Elsevier
Nanomedicine is a fast evolving field involving nanoparticles or nanostructures for medical
applications. Especially in the underdeveloped field of drug delivery to the brain, there are …
applications. Especially in the underdeveloped field of drug delivery to the brain, there are …