Congenital heart disease (CHD) is present in approximately 50% of patients with trisomy 21
(T21) and Turner syndrome (TS). According to the American Academy of Pediatrics, every …

Trisomy 18 (T18) is the second most common autosomal trisomy after trisomy 21 (T21). More
than 90% of patients with T18 have congenital heart disease (CHD). Patients with T18 also …

Congenital heart defects (CHD) are very common in patients with trisomy 18 (T18) and
trisomy 13 (T13). The surgical indication of CHD remains controversial since the natural …

Abstract Background Patients with Trisomy 21 are now living well into adulthood. Little data
exists to assist the cardiologist in the care of these patients. We sought to examine the …

Objective To evaluate long-term transplant-free survival and causes of death in the trisomy
21 (T21) population after surgery for congenital heart disease (CHD) in comparison with …

As the care and management of congenital heart disease changed in trisomy 21, so too it
has with trisomy 13 and 18. Physicians and parents should develop goal-directed treatment …

Background Congenital heart disease is common in patients with Trisomy 13 (T13) and
Trisomy 18 (T18), but offering cardiac surgery to these patients has been controversial. We …

Background: In patients with trisomy 18, congenital heart surgery is controversial due to
anticipated poor patient outcome. Data are lacking regarding clinical outcomes and family …

Trisomy 18 (Edwards syndrome) is the second most common autosomal trisomy after
trisomy 21. Medical issues commonly include cardiac defects, such as ventricular septal …

The population of neonates and children with congenital heart defects presents about a 30%
prevalence of associated genetic syndrome or additional extracardiac anomalies and may …