Chagas disease is a chronic systemic infection transmitted by Trypanosoma cruzi. Its life
cycle consists of different stages in vector insects and host mammals. Trypanosoma cruzi …

Pathophysiology of Chagas' disease is not completely defined, although innate and
adaptative immune responses are crucial. In acute infection some parasite antigens can …

The major goal of studies on immunity to Trypanosoma cruzi is the understanding of
immunological mechanisms involved in resistance to this protozoan as well as the …

Abstract Trypanosoma cruzi (T. cruzi), the etiological agent of Chagas disease, affects nearly
18 million people in Latin America and 90 million are at risk of infection. The parasite …

Introduction• Chagas' disease• Chemotherapy• Immune response in experimental T. cruzi
infection• Immune response in human beings infected with T. cruzi• Immune response in the …

Trypanosoma cruzi interacts with the different arms of the innate and adaptive host's immune
response in a very complex and flowery manner. The history of host-parasite co-evolution …

Current understanding of key cellular pathways, which are activated by the interaction
between T. cruzi and host immunity, is crucial for controlling T. cruzi infection and also for …

Chagas disease is associated with several immunological alterations. Although resistance
against infection with Trypanosoma cruzi has been shown to be influenced by the immune …

Chagas disease is caused by the protozoan Trypanosoma cruzi. The parasite reaches the
secondary lymphoid organs, the heart, skeletal muscles, neurons in the intestine and …

The protozoan Trypanosoma cruzi is the causative agent of Chagas' disease, endemic in
Latin America but present worldwide. Research efforts have focused on the examination of …