TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1
KK McDonald, A Aulas… - Human molecular …, 2011 - academic.oup.com
TAR deoxyribonucleic acid-binding protein 43 (TDP-43) is a multifunctional protein with
roles in transcription, pre-messenger ribonucleic acid (mRNA) splicing, mRNA stability and …
roles in transcription, pre-messenger ribonucleic acid (mRNA) splicing, mRNA stability and …
[HTML][HTML] Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue
L Liu-Yesucevitz, A Bilgutay, YJ Zhang, T Vanderwyde… - PloS one, 2010 - journals.plos.org
Tar DNA Binding Protein-43 (TDP-43) is a principle component of inclusions in many cases
of frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). TDP …
of frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). TDP …
[HTML][HTML] Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43
TAR DNA-binding protein-43 (TDP-43) has been recently identified as a major component of
the ubiquitinated inclusions found in frontotemporal lobar degeneration with ubiquitin …
the ubiquitinated inclusions found in frontotemporal lobar degeneration with ubiquitin …
TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor
CM Dewey, B Cenik, CF Sephton… - … and cellular biology, 2011 - Taylor & Francis
TDP-43, or TAR DNA-binding protein 43, is a pathological marker of a spectrum of
neurodegenerative disorders, including amyotrophic lateral sclerosis and frontotemporal …
neurodegenerative disorders, including amyotrophic lateral sclerosis and frontotemporal …
[HTML][HTML] TDP-43: gumming up neurons through protein–protein and protein–RNA interactions
E Buratti, FE Baralle - Trends in biochemical sciences, 2012 - cell.com
Since the discovery that 43 kDa TAR DNA binding protein (TDP-43) is involved in
neurodegeneration, studies of this protein have focused on the global effects of TDP-43 …
neurodegeneration, studies of this protein have focused on the global effects of TDP-43 …
[HTML][HTML] Aggregation of the nucleic acid–binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation
TAR DNA-binding protein 43 (TDP-43) is a nucleic acid–binding protein, and its aggregation
represents the defining pathology in amyotrophic lateral sclerosis (ALS) and related …
represents the defining pathology in amyotrophic lateral sclerosis (ALS) and related …
TDP-43 in central nervous system development and function: clues to TDP-43-associated neurodegeneration
From the earliest stages of embryogenesis and throughout life, transcriptional regulation is
carefully orchestrated in order to generate, shape, and reshape the central nervous system …
carefully orchestrated in order to generate, shape, and reshape the central nervous system …
[HTML][HTML] Stress induced TDP-43 mobility loss independent of stress granules
L Streit, T Kuhn, T Vomhof, V Bopp, AC Ludolph… - Nature …, 2022 - nature.com
Abstract TAR DNA binding protein 43 (TDP-43) is closely related to the pathogenesis of
amyotrophic lateral sclerosis (ALS) and translocates to stress granules (SGs). The role of …
amyotrophic lateral sclerosis (ALS) and translocates to stress granules (SGs). The role of …
[HTML][HTML] Aberrant assembly of RNA recognition motif 1 links to pathogenic conversion of TAR DNA-binding protein of 43 kDa (TDP-43)
A Shodai, T Morimura, A Ido, T Uchida, T Ayaki… - Journal of Biological …, 2013 - ASBMB
Aggregation of TAR DNA-binding protein of 43 kDa (TDP-43) is a pathological signature of
amyotrophic lateral sclerosis (ALS). Although accumulating evidence suggests the …
amyotrophic lateral sclerosis (ALS). Although accumulating evidence suggests the …
[HTML][HTML] Cellular model of TAR DNA-binding protein 43 (TDP-43) aggregation based on its C-terminal Gln/Asn-rich region
TDP-43 is one of the major components of the neuronal and glial inclusions observed in
several neurodegenerative diseases such as amyotrophic lateral sclerosis and …
several neurodegenerative diseases such as amyotrophic lateral sclerosis and …
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