Polyuria–polydipsia syndrome can be caused by central diabetes insipidus, nephrogenic
diabetes insipidus or primary polydipsia. To avoid confusion with diabetes mellitus, the …

Arginine vasopressin (AVP) deficiency (central diabetes insipidus [DI]), AVP resistance
(nephrogenic DI), and primary polydipsia are difficult to distinguish clinically. Water …

Background Distinguishing between arginine vasopressin (AVP) deficiency and primary
polydipsia is challenging. Hypertonic saline–stimulated copeptin has been used to diagnose …

Arginine vasopressin deficiency (AVP-D) is one of the main entities of the polyuria-
polydipsia syndrome. Its correct diagnosis and differentiation from the other two causes-AVP …

Diabetes insipidus (DI) is a disorder characterised by the excretion of large amounts of
hypotonic urine, with a prevalence of 1 per 25,000 population. Central DI (CDI), better now …

Central diabetes insipidus (CDI) is a clinical syndrome which results from loss or impaired
function of vasopressinergic neurons in the hypothalamus/posterior pituitary, resulting in …

Accurate classification of patients with hypotonic polyuria is essential because management
differs for the three main causes1: arginine vasopressin (AVP) deficiency (formerly called …

Diabetes insipidus (DI) is characterized by polyuria and polydipsia. It can be caused either
by deficit of vasopressin (central DI) or by renal resistance to its action (nephrogenic DI). The …

The water deprivation test is the gold standard test to differentiate central or nephrogenic
diabetes insipidus (DI) from primary polydipsia (PP) in patients with polyuria and polydipsia …

Diabetes insipidus (DI), be it from central or nephrogenic origin, must be differentiated from
secondary forms of hypotonic polyuria such as primary polydipsia. Differentiation is crucial …