Recent advances of rotavirus (RV) basic and applied research are reviewed. They consist of
determination of the RV particle structure and functions of structural proteins, classification …

A safe and effective rotavirus vaccine is urgently needed, particularly in developing
countries. Critical to vaccine development and implementation is a knowledge base …

The pathogenicity of rotaviruses depends on multiple viral and host factors. In this review the
evidence for the involvement of a number of viral genes in the ability to cause disease is …

Since its discovery 40 years ago, rotavirus (RV) is considered to be a major cause of infant
and childhood morbidity and mortality particularly in developing countries. Nearly every …

Publisher Summary Human group A rotaviruses were first identified by Bishop et al. in 1973.
In the ensuing 15 years, a great deal was learned about these important pathogens …

Knowledge of the structure and function of the genes and proteins of the rotaviruses has
expanded rapidly. Information obtained in the last 5 years has revealed unexpected and …

Rotaviruses are the major cause of severe gastroenteritis in young children and animals.
The rotavirus genome is composed of eleven segments of double-stranded RNA and can …

Rotaviruses are a leading cause of viral acute gastroenteritis in humans and animals. Eight
different rotavirus species (A–H) have been defined based on antigenicity and nucleotide …

Rotaviruses (RVs) are a large genetically diverse population of segmented double-stranded
(ds) RNA viruses that are important causes of gastroenteritis in many animal species. The …

In April 2008, a nucleotide-sequence-based, complete genome classification system was
developed for group A rotaviruses (RVs). This system assigns a specific genotype to each of …