Cancer is probably the deadliest human disease in recent years. In the past few years, rapid
clinical progress has been made in the field of anticancer drug development. Plant …

Nothapodytes nimmoniana is an endangered medicinal plant widely distributed throughout
the Western Ghats of India. The plant contains camptothecin (CPT) which is renowned …

Camptothecin (CPT) is a monoterpenoid-alkaloid, an anticancer compound from plant. Ever
since its discovery in 1996 from the bark of Camptotheca acuminata, various researches …

Camptothecin (CPT) is mainly produced and extracted from Camptotheca acuminata and
Nothapodytes foetida for pharmaceutical use, ie, the starting material for chemical …

The horrifying impact of emergence of cancer as an endemic disease worldwide associated
with accelerated mortality rate caused significant boost in anticancer drug discovery. The …

The plant Nothapodytes nimmoniana belongs to the Icacinaceae family, and is a significant
source of camptothecin (CPT), an effective quinoline alkaloid with an array of …

Camptothecin (CPT) is a water insoluble and cytotoxic monoterpene indole alkaloid, which
is used as the substrate to form water-soluble derivatives (such as topotecan and irinotecan) …

Camptothecin (CPT) is a kind of modified monoterpene indole alkaloid firstly identified from
woody plant Camptotheca acuminata, and its semisynthetic CPT analogs irinothecan and …

Since the first report on Camptothecin detection in Nothapodytes nimmoniana by
Govindachari and Viswanathan (Phytochem 11: 35–29, 1972), considerable work has been …

Callus cultures were established from excised embryos of Nothapodytes foetida on
Murashige and Skoog medium supplemented with picloram (2 mg l− 1) and 3%(w/v) …