[HTML][HTML] Inflammation, microbiome and colorectal cancer disparity in African-Americans: Are there bugs in the genetics?

S Ahmad, H Ashktorab, H Brim… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Dysregulated interactions between host inflammation and gut microbiota over the course of
life increase the risk of colorectal cancer (CRC). While environmental factors and socio …

[HTML][HTML] Gut microbiome profiling and colorectal cancer in African Americans and Caucasian Americans

L Farhana, F Antaki, F Murshed… - World journal of …, 2018 - ncbi.nlm.nih.gov
AIM To determine whether and to what extent the gut microbiome is involved in regulating
racial disparity in colorectal cancer (CRC). METHODS All patients were recruited and …

Associations between the Gut Microbiota, Race, and Ethnicity of Patients with Colorectal Cancer: A Pilot and Feasibility Study

S Piawah, TS Kyaw, K Trepka, AL Stewart, RV Mora… - Cancers, 2023 - mdpi.com
Simple Summary The trillions of microorganisms found in the human gut have broad impacts
on health and disease including altering the risk of colorectal cancer. Given the emerging …

The impact of the gut microbiome on colorectal cancer

C Maisonneuve, T Irrazabal, A Martin… - Annual Review of …, 2018 - annualreviews.org
Colorectal cancer (CRC) represents one of the leading causes of morbidity and cancer-
related mortality in the world. While the etiology of CRC is believed to arise from genetic …

A case–control study of the association between the gut microbiota and colorectal cancer: exploring the roles of diet, stress, and race

TL Carson, DA Byrd, KS Smith, D Carter, M Gomez… - Gut Pathogens, 2024 - Springer
Background The gut microbiota is associated with risk for colorectal cancer (CRC), a chronic
disease for which racial disparities persist with Black Americans having a higher risk of CRC …

The multifaceted role of the intestinal microbiota in colon cancer

T Irrazábal, A Belcheva, SE Girardin, A Martin… - Molecular cell, 2014 - cell.com
In recent years, our understanding of the mechanisms underlying colorectal carcinogenesis
has vastly expanded. Underlying inflammation within the intestine, diet, and most recently …

[HTML][HTML] Race, the microbiome and colorectal cancer

KJ Royston, B Adedokun… - World Journal of …, 2019 - ncbi.nlm.nih.gov
In the past decade, more cancer researchers have begun to understand the significance of
cancer prevention, which has prompted a shift in the increasing body of scientific literature …

[HTML][HTML] Microbiome and colorectal carcinogenesis: linked mechanisms and racial differences

SC Tortora, VM Bodiwala, A Quinn… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Various studies have shown the interplay between the intestinal microbiome, environmental
factors, and genetic changes in colorectal cancer (CRC) development. In this review, we …

Clinical and genetic factors to inform reducing colorectal cancer disparitites in African Americans

JM Carethers - Frontiers in Oncology, 2018 - frontiersin.org
Colorectal cancer (CRC) is the third most prevalent and second deadliest cancer in the US
with 140,250 cases and 50,630 deaths for 2018. Prevention of CRC through screening is …

Chronic intestinal inflammation: inflammatory bowel disease and colitis-associated colon cancer

DC Rubin, A Shaker, MS Levin - Frontiers in immunology, 2012 - frontiersin.org
The inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative
colitis (UC), are chronic inflammatory disorders of the intestine. The prevalence in the United …