Hypoxia is the failure of oxygenation at the tissue level, where the reduced oxygen delivered
is not enough to satisfy tissue demands. Metabolic depression is the physiological …

Molecular oxygen is vital to the survival of all mammalian tissues, serving as the terminal
electron acceptor in the oxidative process that provides the usable energy necessary for life …

In clinical settings, oxygen therapy is administered to preterm neonates and to adults with
acute and chronic conditions such as COVID-19, pulmonary fibrosis, sepsis, cardiac arrest …

Hypoxia induces several responses at cardiovascular, pulmonary and reproductive levels,
which may lead to chronic diseases. This is relevant in human populations exposed to high …

Increased production and buildup of reactive oxygen species (ROS) can lead to various
health issues, including metabolic problems, cancers, and neurological conditions. Our …

Since cyanobacteria began to photosynthesize and introduce the colorless and odorless
gas oxygen into the earth's atmosphere some 2.5 billion years ago, human evolution has …

Hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of morbidity and
mortality in neonates. Because of high concentrations of sensitive immature cells, metal …

Hypoxia and its corollaries pose both negative and positive pressures to multicellular
eukaryotes. Evolutionarily, life developed under hypoxia, and the building blocks were …

Oxidative Stress: Eustress and Distress presents current knowledge on oxidative stress
within the framework of redox biology and translational medicine. It describes eustress and …

Oxidative stress is associated with the onset and pathogenesis of several prominent central
nervous system disorders. Consequently, there is a pressing need for experimental methods …