Perineuronal nets: plasticity, protection, and therapeutic potential
The relationship between neurons and perineuronal nets (PNNs) is attracting attention as a
central mechanism controlling brain plasticity. In the cortex, PNNs primarily surround …
central mechanism controlling brain plasticity. In the cortex, PNNs primarily surround …
Regulation of perineuronal nets in the adult cortex by the activity of the cortical network
G Devienne, S Picaud, I Cohen, J Piquet… - Journal of …, 2021 - Soc Neuroscience
Perineuronal net (PNN) accumulation around parvalbumin-expressing (PV) inhibitory
interneurons marks the closure of critical periods of high plasticity, whereas PNN removal …
interneurons marks the closure of critical periods of high plasticity, whereas PNN removal …
The perineuronal net and the control of CNS plasticity
D Wang, J Fawcett - Cell and tissue research, 2012 - Springer
Perineuronal nets (PNNs) are reticular structures that surround the cell body of many
neurones, and extend along their dendrites. They are considered to be a specialized …
neurones, and extend along their dendrites. They are considered to be a specialized …
Removal of perineuronal nets unlocks juvenile plasticity through network mechanisms of decreased inhibition and increased gamma activity
KK Lensjø, ME Lepperød, G Dick… - Journal of …, 2017 - Soc Neuroscience
Perineuronal nets (PNNs) are extracellular matrix structures mainly enwrapping
parvalbumin-expressing inhibitory neurons. The assembly of PNNs coincides with the end of …
parvalbumin-expressing inhibitory neurons. The assembly of PNNs coincides with the end of …
Perineuronal nets suppress plasticity of excitatory synapses on CA2 pyramidal neurons
Long-term potentiation of excitatory synapses on pyramidal neurons in the stratum radiatum
rarely occurs in hippocampal area CA2. Here, we present evidence that perineuronal nets …
rarely occurs in hippocampal area CA2. Here, we present evidence that perineuronal nets …
[HTML][HTML] Impact of perineuronal nets on electrophysiology of parvalbumin interneurons, principal neurons, and brain oscillations: a review
JC Wingert, BA Sorg - Frontiers in synaptic neuroscience, 2021 - frontiersin.org
Perineuronal nets (PNNs) are specialized extracellular matrix structures that surround
specific neurons in the brain and spinal cord, appear during critical periods of development …
specific neurons in the brain and spinal cord, appear during critical periods of development …
[HTML][HTML] The perineuronal 'safety'net? Perineuronal net abnormalities in neurological disorders
Perineuronal nets (PNN) are extracellular matrix (ECM) assemblies that preferentially
ensheath parvalbumin (PV) expressing interneurons. Converging evidence indicates that …
ensheath parvalbumin (PV) expressing interneurons. Converging evidence indicates that …
Perineuronal nets control visual input via thalamic recruitment of cortical PV interneurons
In the neocortex, critical periods (CPs) of plasticity are closed following the accumulation of
perineuronal nets (PNNs) around parvalbumin (PV)-positive inhibitory interneurons …
perineuronal nets (PNNs) around parvalbumin (PV)-positive inhibitory interneurons …
Perineuronal nets in brain physiology and disease
D Testa, A Prochiantz, AA Di Nardo - Seminars in cell & developmental …, 2019 - Elsevier
Perineuronal nets (PNNs) in the brain are condensed glycosaminoglycan-rich extracellular
matrix structures with heterogeneous composition yet specific organization. They typically …
matrix structures with heterogeneous composition yet specific organization. They typically …
[PDF][PDF] A comprehensive atlas of perineuronal net distribution and colocalization with parvalbumin in the adult mouse brain
Perineuronal nets (PNNs) surround specific neurons in the brain and are involved in various
forms of plasticity and clinical conditions. However, our understanding of the PNN role in …
forms of plasticity and clinical conditions. However, our understanding of the PNN role in …
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