Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2
TA Tummino, VV Rezelj, B Fischer, A Fischer… - Science, 2021 - science.org
Repurposing drugs as treatments for COVID-19, the disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has drawn much attention. Beginning …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has drawn much attention. Beginning …
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has …
(SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has …
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019
has triggered an ongoing global pandemic of the severe pneumonia-like disease …
has triggered an ongoing global pandemic of the severe pneumonia-like disease …
Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2
There is an urgent need for antivirals to treat the newly emerged severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). To identify new candidates, we screen a …
syndrome coronavirus 2 (SARS-CoV-2). To identify new candidates, we screen a …
Drug repurposing screens reveal FDA approved drugs active against SARS-Cov-2
There are an urgent need for antivirals to treat the newly emerged SARS-CoV-2. To identify
new candidates we screened a repurposing library of~ 3,000 drugs. Screening in Vero cells …
new candidates we screened a repurposing library of~ 3,000 drugs. Screening in Vero cells …
Statins: could an old friend help in the fight against COVID‐19?
RR Rodrigues‐Diez, A Tejera‐Muñoz… - British journal of …, 2020 - Wiley Online Library
The COVID‐19 pandemic caused by the severe acute respiratory syndrome coronavirus 2
(SARS‐CoV‐2) has overwhelmed healthcare systems requiring the rapid development of …
(SARS‐CoV‐2) has overwhelmed healthcare systems requiring the rapid development of …
Potential COVID-19 therapeutics from a rare disease: weaponizing lipid dysregulation to combat viral infectivity
SL Sturley, T Rajakumar, N Hammond, K Higaki… - Journal of lipid …, 2020 - ASBMB
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus (SARS-CoV)-2 has resulted in the death of more than 328,000 …
syndrome coronavirus (SARS-CoV)-2 has resulted in the death of more than 328,000 …
Rapid repurposing of drugs for COVID-19
RK Guy, RS DiPaola, F Romanelli, RE Dutch - Science, 2020 - science.org
In late fall 2019, a novel acute respiratory disease, called coronavirus disease 2019 (COVID-
19) emerged in Wuhan, China. COVID-19 is caused by severe acute respiratory syndrome …
19) emerged in Wuhan, China. COVID-19 is caused by severe acute respiratory syndrome …
Repurposing sigma-1 receptor ligands for COVID-19 therapy?
JM Vela - Frontiers in Pharmacology, 2020 - frontiersin.org
Outbreaks of emerging infections, such as COVID-19 pandemic especially, confront health
professionals with the unique challenge of treating patients. With no time to discover new …
professionals with the unique challenge of treating patients. With no time to discover new …
Phosphatidylserine receptors enhance SARS-CoV-2 infection
D Bohan, H Van Ert, N Ruggio, KJ Rogers… - PLoS …, 2021 - journals.plos.org
Phosphatidylserine (PS) receptors enhance infection of many enveloped viruses through
virion-associated PS binding that is termed apoptotic mimicry. Here we show that this …
virion-associated PS binding that is termed apoptotic mimicry. Here we show that this …