Salivary glands sustain collateral damage following radiotherapy (RT) to treat cancers of the
head and neck, leading to complications, including mucositis, xerostomia and …

Radiation therapy for head and neck cancer causes significant secondary side-effects in
normal salivary glands, resulting in diminished quality of life for these individuals. Salivary …

When considering the effects of drugs on salivary glands, a distinction should be drawn
between the complaint of oral dryness (xerostomia), a symptom, and measurable secretory …

Purpose This review addressed the structural changes observed in salivary glands and
pathogenic mechanisms resulting from oxidative stress caused by radiotherapy. The …

Purpose: To contribute to the understanding of the enigmatic radiosensitivity of the salivary
glands by analysis of appropriate literature, especially with respect to mechanisms of action …

Background The most manifest long-term consequences of radiation therapy in the head
and neck cancer patient are salivary gland hypofunction and a sensation of oral dryness …

The most significant long-term complication of radiotherapy in the head-and-neck region is
hyposalivation and its related complaints, particularily xerostomia. This review addresses …

Radiation‐induced hyposalivation is still a major problem after radiotherapy for head and
neck cancer. Current and promising new thoughts to reduce or salvage radiation damage to …

Radiation therapy for cancer of the head and neck can devastate the salivary glands and
partially devitalize the mandible and maxilla. As a result, saliva production is drastically …

This study explored the feasibility of developing an animal model for radiation-induced
salivary gland injury with a radiation protocol identical to current clinical practice. Three male …