We developed a pH-activatable cell-penetrating peptide dimer LH 2 with histidine residues,
which can penetrate cells, specifically in weak acidic conditions, even at few tens of …

Cell‐penetrating peptides (CPP s) have been considered as potential drug delivery vectors
due to their remarkable membrane translocation capacity. However, lack of specificity and …

TP10–5 (TK) was screened as the most promising candidate among the designed
analogues of transportan 10 (TP10), a cell penetrating peptide (CPP) with remarkable …

Abstract TH (AGYLLGHINLHHLAHL (Aib) HHIL-NH 2), a histidine-rich, cell-penetrating
peptide with acid-activated pH response, designed and synthesized by our group, can …

ABSTRACT Purpose Cell penetrating peptides (CPPs) can mediate effective delivery of their
associated drugs and drug carriers intracellularly, however their lack of cell specificity …

Cell penetrating peptides (CPPs) have been well established as potential carriers for
intracellular delivery of protein/peptide therapeutics. However, their lack of selectivity …

To ameliorate the deficiencies (eg solubility, membrane permeability and non-selective
cytotoxicity) of paclitaxel (PTX), we synthesized a “smart” PDC (peptide-drug conjugate), by …

The distinct ability of cell-penetrating peptides (CPPs) has led to the development of novel
drug delivery methods in human cells for therapeutic purposes. The lack of specific …

Cell-penetrating peptides (CPPs) are arginine/lysine-rich sequences, and they are
effectively internalized into cells. In this process, positive charge is crucial. In the present …

Tumor-oriented nanocarrier drug delivery approaches with pH-sensitivity have been
drawing considerable attentions over the years. Here we described a liposomal delivery …