Molecular physiology of pituitary development: signaling and transcriptional networks

X Zhu, AS Gleiberman… - Physiological …, 2007 - journals.physiology.org
The pituitary gland is a central endocrine organ regulating basic physiological functions,
including growth, the stress response, reproduction, metabolic homeostasis, and lactation …

Transcriptional control during mammalian anterior pituitary development

JJ Savage, BC Yaden, P Kiratipranon, SJ Rhodes - Gene, 2003 - Elsevier
The mammalian anterior pituitary gland is a compound endocrine organ that regulates
reproductive development and fitness, growth, metabolic homeostasis, the response to …

Signaling and transcriptional mechanisms in pituitary development

JS Dasen, MG Rosenfeld - Annual review of neuroscience, 2001 - annualreviews.org
▪ Abstract During the development of the pituitary gland, distinct hormone-producing cell
types arise from a common population of ectodermal progenitors, providing an instructive …

[HTML][HTML] A model for the development of the hypothalamic–pituitary axis: transcribing the hypophysis

C Kioussi, C Carriere, MG Rosenfeld - Mechanisms of development, 1999 - Elsevier
Mammalian organogenesis involves a sequential program to generate cells with specific
fates and phenotypes from a common primordium, which is hypothesized to be the …

Development of the pituitary gland

KS Alatzoglou, LC Gregory… - Comprehensive …, 2020 - discovery.ucl.ac.uk
The development of the anterior pituitary gland occurs in distinct sequential developmental
steps, leading to the formation of a complex organ containing five different cell types …

Pituitary development: regulatory codes in mammalian organogenesis

KM Scully, MG Rosenfeld - Science, 2002 - science.org
During mammalian pituitary gland development, distinct cell types emerge from a common
primordium. Appearance of specific cell types occurs in response to opposing signaling …

Perspective: genetic and genomic approaches in elucidating mechanisms of pituitary development

LE Olson, MG Rosenfeld - Endocrinology, 2002 - academic.oup.com
Emergence of distinct cell types from a common primordium during pituitary development
occurs in response to opposing signaling gradients that induce an overlapping temporal and …

Genetic control of pituitary development and hypopituitarism

X Zhu, CR Lin, GG Prefontaine, J Tollkuhn… - Current opinion in …, 2005 - Elsevier
The pituitary gland functions as a relay between the hypothalamus and peripheral target
organs that regulate basic physiological functions, including growth, the stress response …

Molecular mechanisms of pituitary organogenesis: in search of novel regulatory genes

SW Davis, F Castinetti, LR Carvalho… - Molecular and cellular …, 2010 - Elsevier
Defects in pituitary gland organogenesis are sometimes associated with congenital
anomalies that affect head development. Lesions in transcription factors and signaling …

Multistep signaling requirements for pituitary organogenesis in vivo

M Treier, AS Gleiberman, SM O'Connell… - Genes & …, 1998 - genesdev.cshlp.org
During development of the mammalian pituitary gland specific hormone-producing cell
types, critical in maintaining homeostasis, emerge in a spatially and temporally specific …