Implementing pharmacogenomics in Europe: design and implementation strategy of the ubiquitous pharmacogenomics consortium
CH van der Wouden… - Clinical …, 2017 - Wiley Online Library
Despite scientific and clinical advances in the field of pharmacogenomics (PGx), application
into routine care remains limited. Opportunely, several implementation studies and …
into routine care remains limited. Opportunely, several implementation studies and …
Global pharmacogenomics within precision medicine: challenges and opportunities
MJ Chenoweth, KM Giacomini… - Clinical …, 2020 - Wiley Online Library
This commentary focuses on challenges to the widespread adoption of pharmacogenomics,
outlining issues that need to be addressed ranging from basic pharmacogenomics research …
outlining issues that need to be addressed ranging from basic pharmacogenomics research …
User considerations in assessing pharmacogenomic tests and their clinical support tools
G Mukerjee, A Huston, B Kabakchiev… - NPJ genomic …, 2018 - nature.com
Pharmacogenomic (PGx) testing is gaining recognition from physicians, pharmacists and
patients as a tool for evidence-based medication management. However, seemingly similar …
patients as a tool for evidence-based medication management. However, seemingly similar …
Pharmacogenomics decision support in the U-PGx project: Results and advice from clinical implementation across seven European countries
Background The clinical implementation of pharmacogenomics (PGx) could be one of the
first milestones towards realizing personalized medicine in routine care. However, its …
first milestones towards realizing personalized medicine in routine care. However, its …
Medical education in pharmacogenomics—results from a survey on pharmacogenetic knowledge in healthcare professionals within the European pharmacogenomics …
KS Just, M Steffens, JJ Swen, GP Patrinos… - European journal of …, 2017 - Springer
Purpose Due to the diversity within Europe, the implementation of pharmacogenomic testing
in clinical practice faces specific challenges. In the context of the European …
in clinical practice faces specific challenges. In the context of the European …
Pharmacogenomics in practice: A review and implementation guide
Considerable efforts have been exerted to implement Pharmacogenomics (PGx), the study
of interindividual variations in DNA sequence related to drug response, into routine clinical …
of interindividual variations in DNA sequence related to drug response, into routine clinical …
Estimated nationwide impact of implementing a preemptive pharmacogenetic panel approach to guide drug prescribing in primary care in The Netherlands
PCD Bank, JJ Swen, HJ Guchelaar - BMC medicine, 2019 - Springer
Abstract Background Pharmacogenetics (PGx) is currently implemented in hospitals to
optimize therapy with high-risk drugs. However, many drugs with dosing recommendations …
optimize therapy with high-risk drugs. However, many drugs with dosing recommendations …
Translating pharmacogenomics into clinical decisions: do not let the perfect be the enemy of the good
The field of pharmacogenomics (PGx) is gradually shifting from the reactive testing of single
genes toward the proactive testing of multiple genes to improve treatment outcomes, reduce …
genes toward the proactive testing of multiple genes to improve treatment outcomes, reduce …
Research directions in the clinical implementation of pharmacogenomics: an overview of US programs and projects
S Volpi, CJ Bult, RL Chisholm… - Clinical …, 2018 - Wiley Online Library
Response to a drug often differs widely among individual patients. This variability is
frequently observed not only with respect to effective responses but also with adverse drug …
frequently observed not only with respect to effective responses but also with adverse drug …
The 1200 patients project: creating a new medical model system for clinical implementation of pharmacogenomics
PH O'Donnell, A Bush, J Spitz… - Clinical …, 2012 - Wiley Online Library
The paradigm of individualized drug therapy based on genetics is an ideal that is now
potentially possible. However, translation of pharmacogenomics into practice has …
potentially possible. However, translation of pharmacogenomics into practice has …