Tumor-associated macrophages are strongly related to vascular invasion, non-luminal subtypes, and interval breast cancer

TA Klingen, Y Chen, H Aas, E Wik, LA Akslen - Human pathology, 2017 - Elsevier
Tumor-associated macrophages (TAM) resemble M2 macrophages, promote tumor invasion
and show strong expression of CD163 in breast cancer. We here investigated the …

[HTML][HTML] Tumor-associated macrophages as potential prognostic biomarkers of invasive breast cancer

H Jeong, I Hwang, SH Kang, HC Shin… - Journal of breast …, 2019 - synapse.koreamed.org
Purpose Tumor-associated macrophages (TAMs) are activated macrophages associated
with tumor progression in various cancers. TAMs can polarize M1 or M2 type. M1 has a pro …

[HTML][HTML] CD68-and CD163-positive tumor infiltrating macrophages in non-metastatic breast cancer: a retrospective study and meta-analysis

C Ni, L Yang, Q Xu, H Yuan, W Wang, W Xia… - Journal of …, 2019 - ncbi.nlm.nih.gov
Studies have indicated the significance of tumor associated macrophages (TAMs) in breast
cancer; however, inconsistent results still exist. We retrospectively reviewed the macrophage …

[HTML][HTML] The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients

C Medrek, F Pontén, K Jirström, K Leandersson - BMC cancer, 2012 - Springer
Abstract Background Tumor associated macrophages (TAMs) are alternatively activated
macrophages that enhance tumor progression by promoting tumor cell invasion, migration …

[HTML][HTML] Pathologic evaluation of tumor-associated macrophage density and vessel inflammation in invasive breast carcinomas

Y Morita, R Zhang, M Leslie, S Adhikari… - Oncology …, 2017 - spandidos-publications.com
Tumor-associated macrophages (TAMs) are major constituents of the tumor
microenvironment in solid tumors and have been implicated as mediators of tumor …

[HTML][HTML] High numbers of CD163+ tumor-associated macrophages predict poor prognosis in HER2+ breast cancer

MM Jääskeläinen, R Tumelius, K Hämäläinen, K Rilla… - Cancers, 2024 - mdpi.com
Simple Summary While tumor-associated macrophages (TAMs) are known to be associated
with a poor prognosis in breast cancer (BC) in general, how they influence different BC …

[HTML][HTML] Pathologic assessment of tumor-associated macrophages and their histologic localization in invasive breast carcinoma

SE Mwafy, DM El-Guindy - Journal of the Egyptian National Cancer …, 2020 - Springer
Abstract Background Tumor-associated macrophages (TAMs) are important in regulating
cross-talk between tumor cells and tumor microenvironment. TAMs are involved in multiple …

CD163+ tumor‐associated macrophage accumulation in breast cancer patients reflects both local differentiation signals and systemic skewing of monocytes

RN Ramos, C Rodriguez, M Hubert… - Clinical & …, 2020 - Wiley Online Library
Objectives The accumulation of tumor‐associated macrophages (TAMs) is correlated with
poor clinical outcome, but the mechanisms governing their differentiation from circulating …

[HTML][HTML] Spatial and quantitative analysis of tumor-associated macrophages: intratumoral CD163-/PD-L1+ TAMs as a marker of favorable clinical outcomes in triple …

H Shinohara, M Kobayashi, K Hayashi… - International Journal of …, 2022 - mdpi.com
Tumor-associated macrophages (TAMs) and abnormalities in cancer cells affect cancer
progression and response to therapy. TAMs are a major component of the tumor …

Tumour-infiltrating macrophages and clinical outcome in breast cancer

SMA Mahmoud, AHS Lee, EC Paish… - Journal of clinical …, 2012 - jcp.bmj.com
Background Macrophages constitute a major component of the leucocytic infiltrate of
tumours. Human studies show an association between tumour-associated macrophages …