Sodium tanshinone IIA sulfonate protects rat myocardium against ischemia-reperfusion injury via activation of PI3K/Akt/FOXO3A/Bim pathway
M Zhang, Y Zheng, H Chen, J Tu, YE Shen… - Acta Pharmacologica …, 2013 - nature.com
Aim: To investigate the mechanisms underlying the protective effects of sodium tanshinone
IIA sulfonate (STS) in an ischemia-reperfusion (I/R)-induced rat myocardial injury model …
IIA sulfonate (STS) in an ischemia-reperfusion (I/R)-induced rat myocardial injury model …
Tanshinone IIA protects against myocardial ischemia reperfusion injury by activating the PI3K/Akt/mTOR signaling pathway
Q Li, L Shen, Z Wang, HP Jiang, LX Liu - Biomedicine & pharmacotherapy, 2016 - Elsevier
Objective To determine the mechanism by which Tanshinone IIA (Tan IIA) relieves
myocardial ischemia reperfusion injury (MIRI) in rats via the PI3K/Akt/mTOR signaling …
myocardial ischemia reperfusion injury (MIRI) in rats via the PI3K/Akt/mTOR signaling …
Effect of tanshinone IIA for myocardial ischemia/reperfusion injury in animal model: preclinical evidence and possible mechanisms
PC Zhu, J Shen, RY Qian, J Xu, C Liu, WM Hu… - Frontiers in …, 2023 - frontiersin.org
Introduction: Tanshinone IIA (Tan IIA), the major active lipophilic ingredient of Radix Salviae
Miltiorrhizae, exerts various therapeutic effects on the cardiovascular system. We aimed to …
Miltiorrhizae, exerts various therapeutic effects on the cardiovascular system. We aimed to …
Tanshinone IIA pretreatment protects myocardium against ischaemia/reperfusion injury through the phosphatidylinositol 3‐kinase/Akt‐dependent pathway in diabetic …
Y Zhang, L Wei, D Sun, F Cao, H Gao… - Diabetes, Obesity …, 2010 - Wiley Online Library
Aim: Diabetes Mellitus (DM) is widely acknowledged to increase the risk of cardiovascular
death, which warrants the use of aggressive primary prevention strategies. The aim of the …
death, which warrants the use of aggressive primary prevention strategies. The aim of the …
The cardioprotective effect of sodium tanshinone IIA sulfonate and the optimizing of therapeutic time window in myocardial ischemia/reperfusion injury in rats
B Wei, WW Li, J Ji, QH Hu, H Ji - Atherosclerosis, 2014 - Elsevier
Objective The protective effect of sodium tanshinone IIA sulfonate (STS) pretreatment
against experimental myocardial ischemia/reperfusion (I/R) has been demonstrated …
against experimental myocardial ischemia/reperfusion (I/R) has been demonstrated …
Protective effects of tanshinone IIA on myocardial ischemia reperfusion injury by reducing oxidative stress, HMGB1 expression, and inflammatory reaction
H Hu, C Zhai, G Qian, A Gu, J Liu, F Ying… - Pharmaceutical …, 2015 - Taylor & Francis
Context: Although there were reports on the protective functions of tanshinone IIA (TSA) on
rat myocardial ischemia, the exerting mechanism has not been completely clarified …
rat myocardial ischemia, the exerting mechanism has not been completely clarified …
[HTML][HTML] Protective effects of sodium tanshinone IIA sulfonate on cardiac function after myocardial infarction in mice
P Wu, Y Du, Z Xu, S Zhang, J Liu, N Aa… - American Journal of …, 2019 - ncbi.nlm.nih.gov
Sodium tanshinone IIA sulfonate (STS), a water-soluble derivative of tanshinone IIA, has
been used in traditional Chinese medicine for many years. Many experiments have …
been used in traditional Chinese medicine for many years. Many experiments have …
[HTML][HTML] Protective effects of tanshinone IIA sodium sulfonate on ischemia-reperfusion-induced myocardial injury in rats
Y Pan, JX Qian, SQ Lu, JW Chen, XD Zhao… - Iranian Journal of …, 2017 - ncbi.nlm.nih.gov
Objective (s): This study investigated the protective effect of tanshinone IIA sodium sulfonate
(TSS) on ischemia-reperfusion (I/R) induced cardiac injury, and the underlying mechanism …
(TSS) on ischemia-reperfusion (I/R) induced cardiac injury, and the underlying mechanism …
Sodium tanshinone IIA silate inhibits oxygen‐glucose deprivation/recovery‐induced cardiomyocyte apoptosis via suppression of the NF‐κB/TNF‐α pathway
WY Wu, WY Wang, YL Ma, H Yan… - British Journal of …, 2013 - Wiley Online Library
Background and Purpose Inhibition of apoptosis may attenuate the irreversible injury
associated with reperfusion. In the current study, we focused on the cytoprotective effects …
associated with reperfusion. In the current study, we focused on the cytoprotective effects …
Sodium tanshinone IIA sulfonate protects cardiomyocytes against oxidative stress-mediated apoptosis through inhibiting JNK activation
R Yang, A Liu, X Ma, L Li, D Su… - Journal of cardiovascular …, 2008 - journals.lww.com
Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA, a well-
known Chinese medicine for treating cardiovascular disorders. Cardiomyocyte apoptosis …
known Chinese medicine for treating cardiovascular disorders. Cardiomyocyte apoptosis …
相关搜索
- sodium sulfonate ischemia reperfusion
- rat myocardium ischemia reperfusion
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- sodium tanshinone jnk activation
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- sodium sulfonate protective effects
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- protective effects ischemia reperfusion
- tanshinone iia hmgb1 expression
- tanshinone iia preclinical evidence
- tanshinone iia inflammatory reaction
- tanshinone iia oxidative stress
- myocardial injury ischemia reperfusion