The skin containing melanin pigment acts as a protective barrier and counteracts the UVR
and other environmental stressors to maintain or restore disrupted cutaneous homeostasis …

Melanins are pigment molecules that determine the skin, eye, and hair color of the human
subject to its amount, quality, and distribution. Melanocytes synthesize melanin and provide …

Tyrosinase (EC 1.14. 18.1) is known to be the rate-limiting enzyme responsible for
catalyzing the first two steps in the synthesis of melanin pigments that determine the coloring …

Among the human copper-containing monooxygenases, Tyrosinase (Ty) is an important
enzyme involved in the determinant step of the biosynthetic pathway of melanin pigment. In …

Melanogenesis is simply defined as the production of melanin in melanosomes by
melanocytes through a complex process. Melanin, a pigment derived from L-tyrosine, comes …

Cutaneous pigmentation plays critical role in determining the color of skin along with photo
protection of skin from dreadful effects of ultraviolet radiations. Conversely, abnormal …

Tyrosinase plays a pivotal role in the synthesis of melanin pigment synthesis on skin utilizing
tyrosine as a substrate. Melanin is responsible for the protection against harmful ultraviolet …

Melanin, a major pigment in mammalian skin, is known to protect the skin against harmful
effects of ultraviolet (UV) irradiation, oxidative stress, and DNA damage. The accumulation …

Tyrosinase, a copper-containing glycoprotein, is the rate-limiting enzyme critical for melanin
biosynthesis in specialized organelles termed melanosomes that are produced only by …

Tyrosinase is known to be a key enzyme in melanin biosynthesis, involved in determining
the color of mammalian skin and hair. Various dermatological disorders, such as melasma …