Newly growing evidence highlights the essential role that epitranscriptomic marks play in the
development of many cancers; however, little is known about the role and implications of …

The emerging" epitranscriptomics" field is providing insights into the biological and
pathological roles of different RNA modifications. The RNA methyltransferase METTL1 …

Recently, covalent modifications of RNA, such as methylation, have emerged as key
regulators of all aspects of RNA biology and have been implicated in numerous diseases …

Background The posttranscriptional modifications of transfer RNA (tRNA) are critical for all
aspects of the tRNA function and have been implicated in the tumourigenesis and …

Abstract Background N7‐methylguanosine (m7G) modification is one of the most common
transfer RNA (tRNA) modifications in humans. The precise function and molecular …

Cancer cells selectively promote translation of specific oncogenic transcripts to facilitate
cancer survival and progression, but the underlying mechanisms are poorly understood …

Background: Since primary prostate cancer (PCa) can advance to the life-threatening
metastatic PCa, exploring the molecular mechanisms underlying PCa metastasis is crucial …

Growing evidence indicates that N6-methyladenosine (m 6 A) is the most pervasive RNA
modification in eukaryotic cells. However, the specific role of METTL3 in papillary thyroid …

METTL3 encodes the predominant catalytic enzyme to promote m6A methylation in nucleus.
Recently, accumulating evidence has shown the expression of METTL3 in cytoplasm, but its …

Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancers and is
characterized by high recurrence and heterogeneity, yet its mechanism is not well …