The complement system comprises several fluid-phase and membrane-associated proteins.
Under physiological conditions, activation of the fluid-phase components of complement is …

The complement system consists of both plasma and membrane proteins. The former
influence the inflammatory response, immune modulation, and host defense. The latter are …

Mannose‐binding lectin (MBL) is an important constituent of the innate immune system. This
protein binds through multiple lectin domains to the repeating sugar arrays that decorate …

Mannan‐binding lectin (MBL) is a plasma collectin (C‐type lectin with a collagen‐like
domain) and is considered an important component of innate immunity. Circulating MBL is …

Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the
ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More …

OBJECTIVE To determine the prevalence of a mannan binding lectin (MBL) deficiency in
children with increased susceptibility to infections and to investigate whether other …

Blood samples were collected over a 4-year period from 335 children (aged 1–16 years)
suffering from recurrent respiratory infections and 78 controls. The patients were subdivided …

Complement deficiency is associated with an increased prevalence of pyogenic infections
and immune complex disease. The spectrum of disease in deficient individuals depends on …

The complement system is a major component of the innate immune system and it provides
a powerful and effective mechanism to protect the host from pathogens. It was first described …

When the adaptive immune response is either immature or compromised, the innate
immune system constitutes the principle defense against infection. Mannose-binding lectin …