[HTML][HTML] Gut microbiome plays a vital role in post-stroke injury repair by mediating neuroinflammation

A Huang, L Ji, Y Li, Y Li, Q Yu - International Immunopharmacology, 2023 - Elsevier
Cerebral stroke is a common neurological disease and often causes severe neurological
deficits. With high morbidity, mortality, and disability rates, stroke threatens patients' life …

The gut ecosystem: a critical player in stroke

R Delgado Jiménez, C Benakis - Neuromolecular medicine, 2021 - Springer
The intestinal microbiome is emerging as a critical factor in health and disease. The
microbes, although spatially restricted to the gut, are communicating and modulating the …

The role of gut microbiota in an ischemic stroke

R Pluta, S Januszewski, SJ Czuczwar - International journal of molecular …, 2021 - mdpi.com
The intestinal microbiome, the largest reservoir of microorganisms in the human body, plays
an important role in neurological development and aging as well as in brain disorders such …

Novel mechanisms and therapeutic targets for ischemic stroke: a focus on gut microbiota

Z Bao, Z Zhang, G Zhou, A Zhang, A Shao… - Frontiers in Cellular …, 2022 - frontiersin.org
Ischemic stroke is the most common type of stroke with limited treatment options. Although
the pathological mechanisms and potential therapeutic targets of ischemic stroke have been …

The influence of gut dysbiosis in the pathogenesis and management of ischemic stroke

SB Chidambaram, AG Rathipriya, AM Mahalakshmi… - Cells, 2022 - mdpi.com
Recent research on the gut microbiome has revealed the influence of gut microbiota (GM)
on ischemic stroke pathogenesis and treatment outcomes. Alterations in the diversity …

New insights into stroke prevention and treatment: gut microbiome

L Zhao, L Yang, Y Guo, J Xiao, J Zhang… - Cellular and Molecular …, 2022 - Springer
Stroke, a lethal neurological disease, accounts for a grave economic burden on society.
Despite extensive basic and clinical studies on stroke prevention, a precise effective …

The gut-brain axis in ischemic stroke: its relevance in pathology and as a therapeutic target

C Benakis, A Liesz - Neurological research and practice, 2022 - Springer
The gut contains the largest reservoir of microorganisms of the human body, termed as the
gut microbiota which emerges as a key pathophysiological factor in health and disease. The …

Crosstalk between gut microbiome and immunology in the management of ischemic brain injury

Z Rahman, MP Dandekar - Journal of Neuroimmunology, 2021 - Elsevier
Ischemic brain injury is a serious neurological complication, which accrues an immense
activation of neuroinflammatory responses. Several lines of research suggested the …

Gut microbiota in acute ischemic stroke: from pathophysiology to therapeutic implications

D Battaglini, PM Pimentel-Coelho, C Robba… - Frontiers in …, 2020 - frontiersin.org
The microbiota–gut–brain axis is considered a central regulator of the immune system after
acute ischemic stroke (AIS), with a potential role in determining outcome. Several pathways …

Gut microbiota in ischemic stroke: role of gut bacteria-derived metabolites

W Zhang, XY Dong, R Huang - Translational stroke research, 2023 - Springer
Ischemic stroke (IS) remains a leading cause of death and long-term disability globally.
Several mechanisms including glutamate excitotoxicity, calcium overload …