Identification of polarized macrophage subsets in zebrafish
M Nguyen-Chi, B Laplace-Builhe, J Travnickova… - Elife, 2015 - elifesciences.org
While the mammalian macrophage phenotypes have been intensively studied in vitro, the
dynamic of their phenotypic polarization has never been investigated in live vertebrates. We …
dynamic of their phenotypic polarization has never been investigated in live vertebrates. We …
Peripheral macrophages promote tissue regeneration in zebrafish by fine-tuning the inflammatory response
RA Morales, ML Allende - Frontiers in immunology, 2019 - frontiersin.org
The role of macrophages during regeneration in zebrafish has been well-documented.
Nevertheless, new evidence indicates that zebrafish macrophages are a heterogeneous …
Nevertheless, new evidence indicates that zebrafish macrophages are a heterogeneous …
RNAseq Profiling of Leukocyte Populations in Zebrafish Larvae Reveals a cxcl11 Chemokine Gene as a Marker of Macrophage Polarization During Mycobacterial …
Macrophages are phagocytic cells from the innate immune system, which forms the first line
of host defense against invading pathogens. These highly dynamic immune cells can adopt …
of host defense against invading pathogens. These highly dynamic immune cells can adopt …
Characterization of zebrafish larval inflammatory macrophages
JR Mathias, ME Dodd, KB Walters, SK Yoo… - Developmental & …, 2009 - Elsevier
Zebrafish have emerged as a powerful model system to study leukocyte recruitment and
inflammation. Here we characterize the morphology and function of inflammatory …
inflammation. Here we characterize the morphology and function of inflammatory …
The Macrophage-Specific Promoter mfap4 Allows Live, Long-Term Analysis of Macrophage Behavior during Mycobacterial Infection in Zebrafish
Transgenic labeling of innate immune cell lineages within the larval zebrafish allows for real-
time, in vivo analyses of microbial pathogenesis within a vertebrate host. To date, labeling of …
time, in vivo analyses of microbial pathogenesis within a vertebrate host. To date, labeling of …
Biology of bony fish macrophages
JW Hodgkinson, L Grayfer, M Belosevic - Biology, 2015 - mdpi.com
Macrophages are found across all vertebrate species, reside in virtually all animal tissues,
and play critical roles in host protection and homeostasis. Various mechanisms determine …
and play critical roles in host protection and homeostasis. Various mechanisms determine …
[HTML][HTML] Cross-organ single-cell transcriptome profiling reveals macrophage and dendritic cell heterogeneity in zebrafish
Tissue-resident macrophages (TRMs) and dendritic cells (DCs) are highly heterogeneous
and essential for immunity, tissue regeneration, and homeostasis maintenance. Here, we …
and essential for immunity, tissue regeneration, and homeostasis maintenance. Here, we …
Conserved gene regulation during acute inflammation between zebrafish and mammals
Zebrafish (Danio rerio), largely used as a model for studying developmental processes, has
also emerged as a valuable system for modelling human inflammatory diseases. However …
also emerged as a valuable system for modelling human inflammatory diseases. However …
Macrophage activation differentially modulates particle binding, phagocytosis and downstream antimicrobial mechanisms
AM Rieger, BE Hall, DR Barreda - Developmental & Comparative …, 2010 - Elsevier
Phagocytosis provides a critical first line of defense against invading pathogens.
Engagement of particles through receptor-mediated binding precedes internalization and …
Engagement of particles through receptor-mediated binding precedes internalization and …
Delineating the roles of neutrophils and macrophages in zebrafish regeneration models
MC Keightley, CH Wang, V Pazhakh… - The international journal …, 2014 - Elsevier
The outcome following injury can be healing, scarring or regeneration, all of which initiate
within a resolving inflammatory response. Regeneration, comprising the complete …
within a resolving inflammatory response. Regeneration, comprising the complete …