In 18 anesthetized dogs with a 70% mechanically produced coronary artery stenosis, blood
flow measured with an electromagnetic flowmeter showed cyclical reductions in flow due to …

Thrombosis on the damaged or ruptured vascular wall in a stenotic coronary artery is
believed to be the precipitating factor leading to unstable angina. Little is known about the …

Aspirin, as an inhibitor of platelet aggregation, may be of benefit in ischemic heart disease.
However, aspirin blocks not only platelet aggregation but also synthesis of prostacyclin, a …

Objectives. The purpose of this study was to assess the antithrombotic potential of various
forms of aspirin administration. Background. Platelet activation in response to endothelial …

The effect of in vitro aspirin treatment and alpha adrenergic receptor stimulation on the
interaction of platelets with the subendothelium was studied using citrated human blood …

The effect of aspirin upon platelet function led to speculation on the potential effects of
salicylates upon arterial thrombogenesis, in which platelets play a primary role. Aspirin was …

We studied the effect of intravenous prostacyclin (PGI 2) infusion on epinephrine
exacerbation of platelet-mediated acute coronary thrombus formation in an in vivo canine …

Aspirin (acetylsalicylic acid) has inhibitory effects on platelet function and prostaglandin
synthesis. Since alterations in either platelet function or prostaglandin-mediated vascular …

Long-Term Inhibition of Platelet Functions by Aspirin Page 1 Long-Term Inhibition of Platelet
Functions by Aspirin1 (34683) ARGON ATAC, MARIO SPAGNUOLO, AND MARJORIE B …

Prostacyclin (PGI2) is a powerful inhibitor of platelet aggregation, but its role in the
pathogenesis of arterial thrombosis is uncertain. We have studied the thrombogenic effect of …