[HTML][HTML] Xenotransplantation: current status in preclinical research

T Lu, B Yang, R Wang, C Qin - Frontiers in immunology, 2020 - frontiersin.org
The increasing life expectancy of humans has led to a growing numbers of patients with
chronic diseases and end-stage organ failure. Transplantation is an effective approach for …

Xenotransplantation: problems and prospects

FH Bach - Annual review of medicine, 1998 - annualreviews.org
Research in xenotransplantation has increased enormously in the last eight years. As the
shortage of allogeneic organs has intensified, the possibility of using organs from pigs has …

Xenotransplantation: current status and a perspective on the future

YG Yang, M Sykes - Nature Reviews Immunology, 2007 - nature.com
Xenotransplantation using pigs as the transplant source has the potential to resolve the
severe shortage of human organ donors. Although the development of relatively non-toxic …

Xenotransplantation of solid organs in the pig-to-primate model

B Ekser, P Rigotti, B Gridelli, DKC Cooper - Transplant immunology, 2009 - Elsevier
Xenotransplantation using pig organs could solve the significant increasing shortage of
donor organs for allotransplantation. In the last two decades, major progress has been made …

[HTML][HTML] Current status of xenotransplantation research and the strategies for preventing xenograft rejection

Q Zhou, T Li, K Wang, Q Zhang, Z Geng… - Frontiers in …, 2022 - frontiersin.org
Transplantation is often the last resort for end-stage organ failures, eg, kidney, liver, heart,
lung, and pancreas. The shortage of donor organs is the main limiting factor for successful …

Current status of xenotransplantation and prospects for clinical application

RN Pierson III, A Dorling, D Ayares… - …, 2009 - Wiley Online Library
Xenotransplantation is one promising approach to bridge the gap between available human
cells, tissues, and organs and the needs of patients with diabetes or end‐stage organ …

Xenotransplantation: immunological hurdles and progress toward tolerance

A Griesemer, K Yamada, M Sykes - Immunological reviews, 2014 - Wiley Online Library
The discrepancy between organ need and organ availability represents one of the major
limitations in the field of transplantation. One possible solution to this problem is …

The immunological barriers to xenotransplantation

M Vadori, E Cozzi - Tissue antigens, 2015 - Wiley Online Library
The availability of cells, tissues and organs from a non‐human species such as the pig
could, at least in theory, meet the demand of organs necessary for clinical transplantation. At …

[HTML][HTML] The resurgence of xenotransplantation

PJ Cowan, AJ Tector - American Journal of transplantation, 2017 - Elsevier
There has been an upsurge of interest in xenotransplantation in recent years. This
resurgence can attributed to a combination of factors. First, there has been a dramatic …

Next steps for the xenotransplantation of pig organs into humans

RA Montgomery, SA Mehta, B Parent, A Griesemer - Nature Medicine, 2022 - nature.com
Next steps for the xenotransplantation of pig organs into humans | Nature Medicine Skip to main
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