[HTML][HTML] Xenotransplantation: current status in preclinical research
T Lu, B Yang, R Wang, C Qin - Frontiers in immunology, 2020 - frontiersin.org
The increasing life expectancy of humans has led to a growing numbers of patients with
chronic diseases and end-stage organ failure. Transplantation is an effective approach for …
chronic diseases and end-stage organ failure. Transplantation is an effective approach for …
Xenotransplantation: problems and prospects
FH Bach - Annual review of medicine, 1998 - annualreviews.org
Research in xenotransplantation has increased enormously in the last eight years. As the
shortage of allogeneic organs has intensified, the possibility of using organs from pigs has …
shortage of allogeneic organs has intensified, the possibility of using organs from pigs has …
Xenotransplantation: current status and a perspective on the future
YG Yang, M Sykes - Nature Reviews Immunology, 2007 - nature.com
Xenotransplantation using pigs as the transplant source has the potential to resolve the
severe shortage of human organ donors. Although the development of relatively non-toxic …
severe shortage of human organ donors. Although the development of relatively non-toxic …
Xenotransplantation of solid organs in the pig-to-primate model
B Ekser, P Rigotti, B Gridelli, DKC Cooper - Transplant immunology, 2009 - Elsevier
Xenotransplantation using pig organs could solve the significant increasing shortage of
donor organs for allotransplantation. In the last two decades, major progress has been made …
donor organs for allotransplantation. In the last two decades, major progress has been made …
[HTML][HTML] Current status of xenotransplantation research and the strategies for preventing xenograft rejection
Transplantation is often the last resort for end-stage organ failures, eg, kidney, liver, heart,
lung, and pancreas. The shortage of donor organs is the main limiting factor for successful …
lung, and pancreas. The shortage of donor organs is the main limiting factor for successful …
Current status of xenotransplantation and prospects for clinical application
RN Pierson III, A Dorling, D Ayares… - …, 2009 - Wiley Online Library
Xenotransplantation is one promising approach to bridge the gap between available human
cells, tissues, and organs and the needs of patients with diabetes or end‐stage organ …
cells, tissues, and organs and the needs of patients with diabetes or end‐stage organ …
Xenotransplantation: immunological hurdles and progress toward tolerance
A Griesemer, K Yamada, M Sykes - Immunological reviews, 2014 - Wiley Online Library
The discrepancy between organ need and organ availability represents one of the major
limitations in the field of transplantation. One possible solution to this problem is …
limitations in the field of transplantation. One possible solution to this problem is …
The immunological barriers to xenotransplantation
M Vadori, E Cozzi - Tissue antigens, 2015 - Wiley Online Library
The availability of cells, tissues and organs from a non‐human species such as the pig
could, at least in theory, meet the demand of organs necessary for clinical transplantation. At …
could, at least in theory, meet the demand of organs necessary for clinical transplantation. At …
[HTML][HTML] The resurgence of xenotransplantation
PJ Cowan, AJ Tector - American Journal of transplantation, 2017 - Elsevier
There has been an upsurge of interest in xenotransplantation in recent years. This
resurgence can attributed to a combination of factors. First, there has been a dramatic …
resurgence can attributed to a combination of factors. First, there has been a dramatic …
Next steps for the xenotransplantation of pig organs into humans
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