Tumor necrosis factor α (TNFα) is a potent immunomodulator and proinflammatory cytokine
that has been implicated in the pathogenesis of autoimmune and infectious diseases. For …

Tumor necrosis factor alpha (TNF alpha) is a central mediator of the immunological
response and the location of the gene within the major histocompatibility complex (MHC) …

Abstract A biallelic G (TNF1 allele) to A (TNF2 allele) polymorphism 308 nucleotides
upstream from the transcription initiation site in the tumor necrosis factor (TNF) promoter is …

Tumor necrosis factor (TNF) is a critical mediator of host defense against infection but may
cause severe pathology when produced in excess. Individuals vary in the amount of TNF …

Tumor necrosis factor-alpha (TNF-α) is a potent immunomediator and proinflammatory
cytokine that has been implicated in the pathogenesis of a large number of human diseases …

The in vitro study of TNF promoter polymorphism (SNP) function was stimulated by the
numerous case–control (association) studies of the polymorphisms in relation to human …

Tumor necrosis factor alpha (TNF-α) promoter polymorphisms have been linked to a large
number of diseases but studies examining the possible direct functional effects of these …

Tumor necrosis factor α (TNFα) is a potent inflammatory cytokine. In human, the TNFα gene
is located within the highly polymorphic major histocompatibility complex (MHC) region on …

Tumour necrosis factor-α (TNF-α) plays a key role in orchestrating the complex events
involved in inflammation and immunity. Accordingly, TNF-α has been implicated in a wide …

Since the tumor necrosis factor alpha (TNF-α) gene was found to be located in the central
major histocompatibility complex (MHC) there has been much speculation concerning a …