Deep computational model for the inference of ventricular activation properties

L Li, J Camps, A Banerjee, M Beetz… - … Workshop on Statistical …, 2022 - Springer
Patient-specific cardiac computational models are essential for the efficient realization of
precision medicine and in-silico clinical trials using digital twins. Cardiac digital twins can …

Deep learning-based emulation of human cardiac activation sequences

A Bertrand, J Camps, V Grau, B Rodriguez - International Conference on …, 2023 - Springer
The vision of digital twins for precision cardiology is to combine expert knowledge and data
of patients' cardiac pathophysiology with advanced computational methods, in order to …

[HTML][HTML] Inference of ventricular activation properties from non-invasive electrocardiography

J Camps, B Lawson, C Drovandi, A Minchole… - Medical Image …, 2021 - Elsevier
The realisation of precision cardiology requires novel techniques for the non-invasive
characterisation of individual patients' cardiac function to inform therapeutic and diagnostic …

Towards enabling cardiac digital twins of myocardial infarction using deep computational models for inverse inference

L Li, J Camps, Z Wang, M Beetz… - … on Medical Imaging, 2024 - ieeexplore.ieee.org
Cardiac digital twins (CDTs) have the potential to offer individualized evaluation of cardiac
function in a non-invasive manner, making them a promising approach for personalized …

Real-time whole-heart electromechanical simulations using latent neural ordinary differential equations

M Salvador, M Strocchi, F Regazzoni, L Dede… - arXiv preprint arXiv …, 2023 - arxiv.org
Cardiac digital twins provide a physics and physiology informed framework to deliver
predictive and personalized medicine. However, high-fidelity multi-scale cardiac models …

Hyper-EP: Meta-learning hybrid personalized models for cardiac electrophysiology

X Jiang, S Vadhavkar, Y Ye, M Toloubidokhti… - arXiv preprint arXiv …, 2024 - arxiv.org
Personalized virtual heart models have demonstrated increasing potential for clinical use,
although the estimation of their parameters given patient-specific data remain a challenge …

[HTML][HTML] Whole-heart electromechanical simulations using Latent Neural Ordinary Differential Equations

M Salvador, M Strocchi, F Regazzoni… - NPJ Digital …, 2024 - nature.com
Cardiac digital twins provide a physics and physiology informed framework to deliver
personalized medicine. However, high-fidelity multi-scale cardiac models remain a barrier to …

Digital twinning of cardiac electrophysiology for congenital heart disease

M Salvador, F Kong, M Peirlinck… - Journal of the …, 2024 - royalsocietypublishing.org
In recent years, blending mechanistic knowledge with machine learning has had a major
impact in digital healthcare. In this work, we introduce a computational pipeline to build …

Cardiac digital twin modeling

A Loewe, P Martínez Díaz, C Nagel… - … treatment strategies for …, 2022 - Springer
A cardiac digital twin is a virtual representation of an individual patient's heart. The
geometric representation of the personalized computational model can be obtained from …

Digital twinning of cardiac electrophysiology models from the surface ECG: a geodesic backpropagation approach

T Grandits, J Verhülsdonk, G Haase… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
The eikonal equation has become an indispensable tool for modeling cardiac electrical
activation accurately and efficiently. In principle, by matching clinically recorded and eikonal …