[HTML][HTML] A Theoretical Essay on Interactions of SARS-CoV-2 Infection with Chronic Obesity Inflammation: an Application of Theoretical Knockouts

GM Favero, LPG Mascarenhas, M Furmann… - Brazilian Archives of …, 2023 - SciELO Brasil
Pathophysiological characteristics of obesity includes chronic inflammation. Complications
in the respiratory tract are related to bodily problems, which lead to a restriction of lung …

The role of obesity in the immunopathogenesis of COVID-19 respiratory disease and critical illness

SJ Kuperberg, B Navetta-Modrov - American journal of respiratory …, 2021 - atsjournals.org
Coronavirus disease (COVID-19), the clinical syndrome caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is currently a global health pandemic with …

[HTML][HTML] Upregulation of inflammatory genes and pathways links obesity to severe COVID-19

J Currey, C Ellsworth, MS Khatun, C Wang… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Obesity is a risk factor for developing severe COVID-19. However, the mechanism
underlying obesity-accelerated COVID-19 remains unclear. Here, we report results from a …

COVID-19 severity in obese patients: Potential mechanisms and molecular targets for clinical intervention

JR Sharma, UCS Yadav - Obesity Research & Clinical Practice, 2021 - Elsevier
With the global spread of SARS-CoV-2, millions of people have been affected leading to the
declaration of coronavirus disease 2019 (COVID-19) as a pandemic by the WHO. Several …

IL-17A and TNF-α as potential biomarkers for acute respiratory distress syndrome and mortality in patients with obesity and COVID-19

JJ Leija-Martinez, F Huang, BE Del-Rio-Navarro… - Medical …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) was declared a pandemic and international
health emergency by the World Health Organization. Patients with obesity with COVID-19 …

[HTML][HTML] Obesity and its impact on COVID-19

AJM de Leeuw, MAM Oude Luttikhuis… - Journal of Molecular …, 2021 - Springer
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has proven
a challenge to healthcare systems since its first appearance in late 2019. The global spread …

Obesity, a major risk factor for immunity and severe outcomes of COVID-19

MT Amin, K Fatema, S Arefin, F Hussain… - Bioscience …, 2021 - portlandpress.com
An influenza-like virus named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2) is responsible for COVID-19 disease and spread worldwide within a short time. COVID-19 …

Potential pathophysiological mechanisms leading to increased COVID-19 susceptibility and severity in obesity

A Belančić, A Kresović, V Rački - Obesity medicine, 2020 - Elsevier
As we are facing worldwide pandemic of COVID-19, we aimed to identify potential
pathophysiological mechanisms leading to increased COVID-19 susceptibility and severity …

[HTML][HTML] Inflammation and oxidative stress, the links between obesity and COVID-19: a narrative review

J Moreno-Fernandez, J Ochoa, ML Ojeda… - Journal of physiology …, 2022 - Springer
COVID-19, an acute respiratory disease caused by SARS-CoV-2, has rapidly become a
pandemic. On the other hand, obesity is also reaching dramatic dimensions and it is a risk …

SARS-CoV-2 infection and obesity: Common inflammatory and metabolic aspects

K Michalakis, I Ilias - Diabetes & Metabolic Syndrome: Clinical Research & …, 2020 - Elsevier
Backround and aims According to the World Obesity Federation,“obesity-related conditions
seem to worsen the effect of Covid-19 (SARS-CoV-2)”; additionally the Centres for Disease …