Metal cation homeostasis is essential for plant nutrition and resistance to toxic heavy metals.
Many plant metal transporters remain to be identified at the molecular level. In the present …

Metal homeostasis is critical for the survival of living organisms, and metal transporters play
central roles in maintaining metal homeostasis in the living cells. We have investigated the …

In contrast with many other essential metals, the mechanisms of Mn acquisition in higher
eukaryotes are seldom studied and poorly understood. We show here that Arabidopsis …

The NRAMP gene family encodes integral membrane protein and mediates the transport of
Fe, however, its function in transport of toxic metal ions is not very clear in plants …

The ability of metal hyperaccumulating plants to tolerate and accumulate heavy metals
results from adaptations of metal homeostasis. NRAMP metal transporters were found to be …

NRAMP (natural resistance-associated macrophage protein) homologues are evolutionarily
conserved bivalent metal transporters. In Arabidopsis, AtNRAMP3 and AtNRAMP4 play a …

Metal transporters regulated by iron can transport a variety of divalent metals, suggesting
that iron regulation is important for specificity of iron transport. In plants, the iron-regulated …

Nramp genes code for a widely distributed class of proteins involved in a variety of
processes, ranging from the control of susceptibility to bacterial infection in mammalian cells …

Each essential transition metal plays a specific role in metabolic processes and has to be
selectively transported. Living organisms need to discriminate between essential and non …

The mammalian Nramp1 protein is an integral membrane protein expressed exclusively in
macrophages, where it plays a critical role in the ability of these cells to destroy ingested …