[HTML][HTML] Fisetin—In search of better bioavailability—From macro to nano modifications: A review

J Szymczak, J Cielecka-Piontek - International Journal of Molecular …, 2023 - mdpi.com
As secondary plant metabolites, polyphenols are abundant in fruits and vegetables. They
are in high demand because of their many health benefits. However, their low bioavailability …

Harnessing the therapeutic potential of fisetin and its nanoparticles: Journey so far and road ahead

S Vishwas, SK Singh, M Gulati, A Awasthi… - Chemico-Biological …, 2022 - Elsevier
Fisetin (FS) is a bioactive flavonoid obtained mostly from apple and strawberry and
classified under the category of food supplements due to numerous pharmacological effects …

[HTML][HTML] Emerging novel drug delivery strategies for bioactive flavonol fisetin in biomedicine

P Mehta, A Pawar, K Mahadik, C Bothiraja - Biomedicine & …, 2018 - Elsevier
Fisetin (FIS), a bioactive flavonol found in the smoke tree (Cotinus coggygria), vegetables,
fruits and nuts. It exhibits various therapeutic activities such as anti-oxidant, anti …

Recent advances in the biosynthesis, structure–activity relationships, formulations, pharmacology, and clinical trials of fisetin

R Zhong, MA Farag, M Chen, C He, J Xiao - EFood, 2022 - Wiley Online Library
Fisetin is one of the most popular flavonoids found in vegetables and fruits with several
health benefits such as antidiabetic, anticancer, and anti‐inflammatory activities …

[HTML][HTML] Folate conjugated albumin as a targeted nanocarrier for the delivery of fisetin: in silico and in vitro biological studies

R Solanki, AK Srivastav, S Patel, SK Singh, B Jodha… - RSC …, 2024 - pubs.rsc.org
Fisetin (FST), a natural flavonoid compound derived from various fruits and vegetables,
including apple, strawberry, and onion, demonstrates potential for a wide range of …

[HTML][HTML] Fisetin in cancer: attributes, developmental aspects, and nanotherapeutics

RM Kumar, H Kumar, T Bhatt, R Jain, K Panchal… - Pharmaceuticals, 2023 - mdpi.com
Cancer is one of the major causes of mortality, globally. Cancerous cells invade normal cells
and metastasize to distant sites with the help of the lymphatic system. There are several …

[HTML][HTML] Fisetin as a senotherapeutic agent: biopharmaceutical properties and crosstalk between cell senescence and neuroprotection

O Elsallabi, A Patruno, M Pesce, A Cataldi, S Carradori… - Molecules, 2022 - mdpi.com
Like other organs, brain functions diminish with age. Furthermore, for a variety of
neurological disorders—including Alzheimer's disease—age is one of the higher-risk …

Therapeutic potential and molecular mechanisms of the multitargeted flavonoid fisetin

A Rauf, T Abu-Izneid, M Imran… - Current Topics in …, 2023 - ingentaconnect.com
Flavonoids effectively treat cancer, inflammatory disorders (cardiovascular and nervous
systems), and oxidative stress. Fisetin, derived from fruits and vegetables, suppresses …

[HTML][HTML] New perspectives for fisetin

G Grynkiewicz, OM Demchuk - Frontiers in chemistry, 2019 - frontiersin.org
Fisetin is a flavonol that shares distinct antioxidant properties with a plethora of other plant
polyphenols. Additionally, it exhibits a specific biological activity of considerable interest as …

Preparation of albumin based nanoparticles for delivery of fisetin and evaluation of its cytotoxic activity

P Ghosh, AS Roy, S Chaudhury, SK Jana… - International journal of …, 2016 - Elsevier
Fisetin is a well known flavonoid that shows several properties such as antioxidant, antiviral
and anticancer activities. Its use in the pharmaceutical field is limited due to its poor aqueous …