Immune response following traumatic spinal cord injury: Pathophysiology and therapies
RC Sterner, RM Sterner - Frontiers in immunology, 2023 - frontiersin.org
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …
significant loss of function and/or permanent disability. The pathophysiology of SCI is …
Inflammation after spinal cord injury: a review of the critical timeline of signaling cues and cellular infiltration
DJ Hellenbrand, CM Quinn, ZJ Piper… - Journal of …, 2021 - Springer
Traumatic spinal cord injury (SCI) is a devastating neurological condition that results in a
loss of motor and sensory function. Although extensive research to develop treatments for …
loss of motor and sensory function. Although extensive research to develop treatments for …
Modulating inflammatory cell responses to spinal cord injury: all in good time
AL Bowes, PK Yip - Journal of neurotrauma, 2014 - liebertpub.com
Spinal cord injury can have a range of debilitating effects, permanently impacting a patient's
quality of life. Initially thought to be an immune privileged site, the spinal cord is able to …
quality of life. Initially thought to be an immune privileged site, the spinal cord is able to …
Modulating the immune response in spinal cord injury
A Ulndreaj, JCT Chio, CS Ahuja… - Expert review of …, 2016 - Taylor & Francis
In spinal cord injury (SCI), the primary mechanical trauma is followed by a secondary injury
cascade which expands the susceptible perilesional region and produces further permanent …
cascade which expands the susceptible perilesional region and produces further permanent …
Inflammation: a target for treatment in spinal cord injury
X Freyermuth-Trujillo, JJ Segura-Uribe… - Cells, 2022 - mdpi.com
Spinal cord injury (SCI) is a significant cause of disability, and treatment alternatives that
generate beneficial outcomes and have no side effects are urgently needed. SCI may be …
generate beneficial outcomes and have no side effects are urgently needed. SCI may be …
Manipulating neuroinflammatory reactions in the injured spinal cord: back to basics
PG Popovich, TB Jones - Trends in pharmacological sciences, 2003 - cell.com
Recruitment of inflammatory leukocytes to the injured spinal cord is a physiological
response that is associated with the production of cytokines and proteinases that are …
response that is associated with the production of cytokines and proteinases that are …
Multiple organ dysfunction and systemic inflammation after spinal cord injury: a complex relationship
X Sun, ZB Jones, X Chen, L Zhou, KF So… - Journal of …, 2016 - Springer
Spinal cord injury (SCI) is a devastating event that results in significant physical disabilities
for affected individuals. Apart from local injury within the spinal cord, SCI patients develop a …
for affected individuals. Apart from local injury within the spinal cord, SCI patients develop a …
Emerging targets for reprograming the immune response to promote repair and recovery of function after spinal cord injury
FH Brennan, PG Popovich - Current opinion in neurology, 2018 - journals.lww.com
Emerging targets for reprograming the immune response to pro... : Current Opinion in Neurology
Emerging targets for reprograming the immune response to promote repair and recovery of …
Emerging targets for reprograming the immune response to promote repair and recovery of …
The pathophysiological role of acute inflammation after spinal cord injury
S Okada - Inflammation and regeneration, 2016 - Springer
Traumatic spinal cord injury (SCI) causes irreparable severe motor and sensory dysfunction.
Mechanical trauma rapidly leads to blood-spinal cord barrier disruption, neural cell death …
Mechanical trauma rapidly leads to blood-spinal cord barrier disruption, neural cell death …
Harmful and beneficial effects of inflammation after spinal cord injury: potential therapeutic implications
Spinal cord injury (SCI) results in immediate damage followed by a secondary phase of
tissue damage that occurs over a period of several weeks. The mechanisms underlying this …
tissue damage that occurs over a period of several weeks. The mechanisms underlying this …
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